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Table 2 Summary of dosimetric results for OARs analyzed from dose-volume histogram

From: Feasibility of a mini-pig model of radiation-induced brain injury to one cerebral hemisphere

 

P1

P2

P3

P4

Summary of dosimetric results for OARs analyzed from dose-volume histogram

Brainstem (Vmean = 3.9 cm3)

D2% (Gy)

22.4

17.7

10.1

10.4

Dmean (Gy)

11.3

9.6

3.6

3.0

V10/12 (%)

53/34

37/20

 < 3.4

 < 3.3

Cerebellum (Vmean = 4.3 cm3)

D2% (Gy)

  

11.1

10.5

Dmean (Gy)

  

3.4

3.4

V10/12 (%)

  

4.6

4.1

Optic chiasm (Vmean = 0.1 cm3)

D2% (Gy)

24.7

23.7

11.0

9.3

Dmean (Gy)

22.9

22.0

10.0

6.7

V6/8/10 (%)

1.0

1.0

 ≤ 1.0

 < 0.5

Left optic nerve (Vmean = 0.1 cm3)

D2% (Gy)

22.1

23.2

10.4

7.4

Dmean (Gy)

17.9

17.4

9.2

6.0

V6/8/10 (%)

1.0

1.0

 ≤ 1.0

 ≤ 0.5

Right optic nerve (Vmean = 0.1 cm3)

D2% (Gy)

20.2

19.1

9.0

4.5

Dmean (Gy)

16.9

14.2

8.3

3.8

V6/8/10 (%)

0.1

0.1

0.1

0.1

Spinal cord (Vmean = 3.7 cm3)

D2% (Gy)

5.5

3.3

 < 1

 < 1

Dmean (Gy)

1.0

0.6

0.2

0.2

V8/10/12 (%)

 < 0.3

0

0

0

Left lens (Vmean = 0.2 cm3)

Dmax (Gy)

3.4

1.4

 < 0.1

 < 0.1

Right lens (Vmean = 0.2 cm3)

Dmax (Gy)

5.6

2.7

1.7

1.5

Brain – PTV (P1&P2) (Vmean = 30 cm3)

D2% (Gy)

22.5

18

  

Dmean (Gy)

11

7.7

  

V10/12 (%)

49/35

52/32

  

Brain – PTV (P3&P4) (Vmean = 36.6 cm3)

D2% (Gy)

  

10.7

11.4

Dmean (Gy)

  

5.3

5.3

V10/12 (%)

  

 ≤ 4

 ≤ 8

  1. Dx% = dose received by the x% of the volume; Dmean = mean dose received by the volume; Vx (VATD) = volume receiving at least x Gy; Vmean = mean structure volume of the four pigs; Dmax = maximum point dose