Utility of adjuvant whole abdominal radiation therapy in ovarian clear cell cancer (OCCC): a pragmatic cohort study of women with classic immuno-phenotypic signature

Stevens, Mark J.; West, Simon; Gard, Gregory; Renaud, Christopher; Nevell, David; Roderick, Stephanie; Le, Andrew

doi:10.1186/s13014-021-01750-4

Table 3 Summary of WART dose volume analysis

From: Utility of adjuvant whole abdominal radiation therapy in ovarian clear cell cancer (OCCC): a pragmatic cohort study of women with classic immuno-phenotypic signature

	Individual DVH parameters					Group DVH parameters
	Patient 1	Patient 2	Patient 3	Patient 4	Patient 5	Min	Max	Median	Mean	SD
PTV_High
D 95% (Gy)	43.40	44.30	43.60	42.49	43.62	42.49	44.30	43.60	43.48	0.65
D 98% (Gy)	42.54	43.50	42.90	41.38	42.63	41.38	43.50	42.63	42.59	0.77
D 2% (Gy)	49.71	48.40	48.10	49.47	48.53	48.10	49.71	48.53	48.84	0.71
D 1% (Gy)	49.99	48.60	48.30	49.77	48.77	48.30	49.99	48.77	49.09	0.75
D 50% (Gy)	47.08	46.80	46.70	46.59	46.33	46.33	47.08	46.70	46.70	0.28
Max	51.23	49.76	49.35	51.69	50.40	49.35	51.69	50.40	50.49	0.98
Min	36.26	38.61	23.49	34.71	35.88	23.49	38.61	35.88	33.79	5.93
Mean	46.79	46.52	46.36	46.28	46.17	46.17	46.79	46.36	46.43	0.24
Length: craniocaudal (cm)	18.60	20.40	18.40	11.40	16.80	11.40	20.40	18.40	17.12	3.44
PTV_Low
D 95% (Gy)	21.74	20.60	17.70	22.94	20.95	17.70	22.94	20.95	20.79	1.95
D 98% (Gy)	21.07	19.40	17.30	22.02	19.43	17.30	22.02	19.43	19.84	1.81
D 2% (Gy)	47.34	46.90	33.70	39.86	40.90	33.70	47.34	40.90	41.74	5.63
D 1% (Gy)	48.34	47.50	38.50	46.27	42.61	38.50	48.34	46.27	44.64	4.07
D 50% (Gy)	25.50	26.10	25.80	26.38	26.43	25.50	26.43	26.10	26.04	0.39
Max	50.21	49.13	48.07	51.38	50.27	48.07	51.38	50.21	49.81	1.26
Min	15.50	13.45	16.25	14.85	11.18	11.18	16.25	14.85	14.24	2.00
Mean	26.47	26.55	25.15	26.91	26.76	25.15	26.91	26.55	26.37	0.70
Length: craniocaudal (cm)	30.00	22.80	20.00	32.80	42.00	20.00	42.00	30.00	29.52	8.70
Kidneys
V 20 Gy (%)	52.27	50.50	44.60	26.44	4.98	4.98	52.27	44.60	35.76	20.02
Mean	19.87	18.53	17.40	17.52	14.40	14.40	19.87	17.52	17.54	2.02
D 2% (Gy)	25.05	26.53	26.40	24.56	20.96	20.96	26.53	25.05	24.70	2.26
D 1% (Gy)	25.30	26.79	26.67	25.17	21.46	21.46	26.79	25.30	25.08	2.16
Kidney L
V 20 Gy (%)	50.26	51.90	44.10	31.41	6.50	6.50	51.90	44.10	36.83	18.77
Mean	19.70	18.69	17.32	17.22	14.70	14.70	19.70	17.32	17.53	1.88
D 2% (Gy)	26.07	26.72	26.34	24.80	21.22	21.22	26.72	26.07	25.03	2.25
D 1% (Gy)	25.16	26.99	26.52	25.24	21.64	21.64	26.99	25.24	25.11	2.10
Kidney R	54.49	49.00	45.10	36.55	3.13
V 20 Gy (%)	19.99	18.37	17.50	18.94	14.16	3.13	54.49	45.10	37.65	20.38
Mean	25.01	26.26	26.50	25.80	20.43	14.16	19.99	18.37	17.79	2.22
D 2% (Gy)	25.30	26.48	27.69	26.22	21.04	20.43	26.50	25.80	24.80	2.51
D 1% (Gy)						21.04	27.69	26.22	25.35	2.55
Kidneys minus PTV
V 20 Gy (%)	36.95	6.07	14.24	26.44	0.58	0.58	36.95	14.24	16.86	14.86
Mean	18.85	13.34	13.37	17.52	12.20	12.20	18.85	13.37	15.06	2.93
D 2% (Gy)	23.41	21.34	23.19	24.56	18.86	18.86	24.56	23.19	22.27	2.23
D 1% (Gy)	23.89	21.86	24.03	25.17	19.64	19.64	25.17	23.89	22.92	2.19
Bladder
V 20 Gy (%)	100.00	100.00	100.00	100.00	99.00	99.00	100.00	100.00	99.80	0.45
V 40 Gy (%)	100.00	100.00	100.00	97.05	0.51	0.51	100.00	100.00	79.51	44.18
V 45 Gy (%)	98.24	99.00	99.70	92.83	0.00	0.00	99.70	98.24	77.95	43.66
Mean	47.43	47.32	46.73	47.00	27.18	27.18	47.43	47.00	43.13	8.92
D 2% (Gy)	49.22	48.79	47.76	49.58	35.99	35.99	49.58	48.79	46.27	5.79
D 1% (Gy)	49.36	48.94	47.87	49.79	38.30	38.30	49.79	48.94	46.85	4.83
Rectum
V 20 Gy (%)	100.00	97.80	100.00	85.63	60.90	60.90	100.00	97.80	88.86	16.74
V 40 Gy (%)	95.49	79.90	98.30	70.18	17.84	17.84	98.30	79.90	72.34	32.57
V 45 Gy (%)	60.10	9.20	15.80	33.82	5.49	5.49	60.10	15.80	24.88	22.50
Mean	44.77	41.37	43.80	38.03	22.77	22.77	44.77	41.37	38.15	8.98
D 2% (Gy)	47.21	45.79	45.94	48.15	46.83	45.79	48.15	46.83	46.78	0.97
D 1% (Gy)	47.29	46.01	46.10	48.27	47.76	46.01	48.27	47.29	47.09	1.00
Liver
V 20 Gy (%)	99.80	82.80	54.80	99.97	99.27	54.80	99.97	99.27	87.33	19.60
Mean	23.66	21.97	20.74	26.31	22.49	20.74	26.31	22.49	23.03	2.11
D 2% (Gy)	26.70	25.78	25.52	32.20	26.30	25.52	32.20	26.30	27.30	2.78
D 1% (Gy)	27.22	26.10	25.80	33.25	27.02	25.80	33.25	27.02	27.88	3.06
PTV_Total
Length: craniocaudal (cm)	44.20	41.80	38.20	43.40	42.00	38.20	44.20	42.00	41.92	2.30
Isocentre Separation (cm)	15.00	10.00	14.00	20.00	15.00	10.00	20.00	15.00	14.80	3.56

PTV, planning target volume; D, dose; Gy, Gray; cm, centimetre; L, left; R, right; V, volume; Min, minimum; Max, maximum; SD, standard deviation

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