Table 4 Toxicity
Acute (n = 101) | Subacute (< 3 months) (n = 82) | > 3 months (n = 72) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Grading | G1 | G2 | G3 | G4 | G5 | G1 | G2 | G3 | G4 | G5 | G1 | G2 | G3 | G4 | G5 |
Toxicity (%) | |||||||||||||||
Dysphagia | 25.7 | 30.7 | 35.6 | 0 | 0 | 30.5 | 22.0 | 9.8 | 0 | 0 | 40.3 | 26.4 | 27.8 | 5.6 | 0 |
Anorexia | 0 | 3.0 | 6.9 | 0 | 0 | 0 | 0 | 1.2 | 0 | 0 | 0 | 1.4 | 2.8 | 0 | 0 |
Nausea/emesis | 18.8 | 18.8 | 14.9 | 0 | 0 | 6.1 | 4.9 | 2.4 | 0 | 0 | 12.5 | 1.4 | 1.4 | 0 | 0 |
Pulmonary toxicity | 5.0 | 12.9 | 4.0 | 0 | 0 | 19.5 | 17.1 | 0 | 0 | 0 | 36.1 | 26.4 | 1.4 | 0 | 0 |
Fistula | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.4 | 0 | 0 | 0 | 0 |
Strictures/bouginage necessary | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 19.4 | 0 | 0 |
Bleeding | 1.0 | 0 | 0 | 0 | 1.0 | 0 | 1.2 | 0 | 0 | 0 | 0 | 1.4 | 1.4 | 0 | 0 |
Dermatitis | 23.8 | 12.9 | 2.0 | 0 | 0 | 6.1 | 1.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Weight loss | 29.7 | 14.9 | 0 | 0 | 0 | 11.0 | 3.7 | 0 | 0 | 0 | 5.6 | 5.6 | 0 | 0 | 0 |
Diarrhea | 74.3 | 19.8 | 5.9 | 0 | 0 | 2.4 | 1.2 | 0 | 0 | 0 | 2.8 | 0 | 0 | 0 | 0 |
Fatigue | 19.8 | 18.8 | 3.0 | 0 | 0 | 13.4 | 6.1 | 3.7 | 0 | 0 | 26.4 | 9.7 | 2.8 | 0 | 0 |
Cardiac toxicity | n/a | 3.7 | 1.2 | 1.2 | 0 | 0 | 5.6 | 1.4 | 0 | 0 | 0 | ||||