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Table 3 Summary of the dose volume histogram analysis for the organs at risk for the node negative patients

From: Treatment planning comparison of volumetric modulated arc therapy employing a dual-layer stacked multi-leaf collimator and helical tomotherapy for cervix uteri

ParameterObjectiveHalcyon (H)Helical Tomotherapy (HT)Difference (H-HT)p
Bowel
 Mean [Gy]Minimise20.5 ± 4.021.0 ± 3.0−0.6 ± 1.70.7
 V40Gy [cm3]≤100 a186.9 ± 115.9224.9 ± 102.2−38.1 ± 22.2< 0.001
 V30Gy [cm3]≤350 a360.9 ± 195.0422.9 ± 134.2−62.1 ± 72.10.02
 V15Gy [cm3]≤600 b1203.8 ± 332.91010.8 ± 320.9192.9 ± 160.40.4
Sigmoid
 D1% [Gy]≤47.346.1 ± 0.546.1 ± 0.8−0.08 ± 0.890.78
Bladder
 D1% [Gy]≤47.346.6 ± 0.246.0 ± 0.30.58 ± 0.28< 0.001
 V40Gy [%]≤75 a50.4 ± 7.052.4 ± 8.3−2.1 ± 6.60.35
 V30Gy [%]≤85 a69.6 ± 5.867.6 ± 7.22.0 ± 8.60.47
Rectum
 D1% [Gy]≤47.346.2 ± 0.446.1 ± 0.60.10 ± 0.890.72
 V40Gy [%]≤85 a80.8 ± 10.888.1 ± 12.3−7.2 ± 11.60.08
 V30Gy [%]≤95 a92.4 ± 6.497.4 ± 3.9−5.0 ± 6.10.03
Left Fem. Head
 D1% [Gy]≤50.038.7 ± 6.932.6 ± 11.76.1 ± 12.70.17
 Mean [Gy]b18.1 ± 2.711.7 ± 0.96.3 ± 2.2< 0.001
Right Fem. Head
 D1% [Gy]≤50.038.5 ± 4.436.5 ± 3.61.9 ± 4.40.20
 Mean [Gy]b18.8 ± 3..311.7 ± 0.96.9 ± 2.7< 0.001
Left Kidney
 Mean [Gy]≤151.5 ± 0.71.5 ± 0.8−0.01 ± 0.320.97
Right Kidney
 Mean [Gy]≤151.5 ± 1.01.6 ± 0.9−0.11 ± 3.70.37
Body
 D1% [Gy]≤47.341.9 ± 1.142.5±0.85 ± 0.590.001
 CI36Gy< 1.6 b1.56 ± 0.081.82 ± 0.19−0.26 ± 0.160.19
 CI43Gy< 1.1 b1.08 ± 0.051.16 ± 0.09−0.08 ± 0.080.09
 CIPaddickb0.91 ± 0.030.86 ± 0.040.05 ± 0.030.03
  1. Vx%: volume receiving at least x% of the dose. Dx%: dose received by at least x% of the volume. CI = conformity index
  2. a: soft constraints, expected to be fulfilled in 70–80% of the patients according to EMBRACE II guidelines
  3. b: not included as optimisation constraint