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Table 5 Excess absolute risk (EAR) (per 10,000 patient-years) of secondary cancer induction estimated with the full model. Results are expressed as average (with 1 standard deviation as uncertainty) and median values

From: Intensity modulated proton therapy compared to volumetric modulated arc therapy in the irradiation of young female patients with hodgkin’s lymphoma. Assessment of risk of toxicity and secondary cancer induction

 RAIMPT∆RA-IMPT)p
Breast12.6 ± 4.93.5 ± 3.39.1 ± 3.2< 0.001
12.22.49.0
Lung22.6 ± 8.015.3 ± 8.07.2 ± 3.7< 0.001
22.815.87.4
Thyroid1.7 ± 1.01.3 ± 1.10.3 ± 0.4< 0.001
1.81.50.2
Esophagus3.4 ± 0.52.6 ± 0.60.8 ± 0.3< 0.001
3.42.50.8
Composite40.2 ± 10.622.7 ± 8.217.5 ± 5.4< 0.001
40.322.516.5
  1. RA RapidArc Volumetric modulated arc therapy, IMPT intensity modulated proton therapy with robust optimization