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Table 5 Excess absolute risk (EAR) (per 10,000 patient-years) of secondary cancer induction estimated with the full model. Results are expressed as average (with 1 standard deviation as uncertainty) and median values

From: Intensity modulated proton therapy compared to volumetric modulated arc therapy in the irradiation of young female patients with hodgkin’s lymphoma. Assessment of risk of toxicity and secondary cancer induction

 

RA

IMPT

∆RA-IMPT)

p

Breast

12.6 ± 4.9

3.5 ± 3.3

9.1 ± 3.2

< 0.001

12.2

2.4

9.0

Lung

22.6 ± 8.0

15.3 ± 8.0

7.2 ± 3.7

< 0.001

22.8

15.8

7.4

Thyroid

1.7 ± 1.0

1.3 ± 1.1

0.3 ± 0.4

< 0.001

1.8

1.5

0.2

Esophagus

3.4 ± 0.5

2.6 ± 0.6

0.8 ± 0.3

< 0.001

3.4

2.5

0.8

Composite

40.2 ± 10.6

22.7 ± 8.2

17.5 ± 5.4

< 0.001

40.3

22.5

16.5

  1. RA RapidArc Volumetric modulated arc therapy, IMPT intensity modulated proton therapy with robust optimization
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Radiation Oncology

ISSN: 1748-717X

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