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Table 1 Patient and tumor characteristics at baseline (n = 9)

From: Axitinib in combination with radiotherapy for advanced hepatocellular carcinoma: a phase I clinical trial

Age, years, median (range)

72 (37–83)

Gender (male: female)

8:1

ECOG performance status

 0

1 (11%)

 1

8 (89%)

Child–Pugh score

 

 5 (class A)

4 (45%)

 6 (class A)

3 (33%)

 7 (class B)

2 (22%)

Etiology of HCC

 Hepatitis B virus (HBV)

5 (56%)

 Hepatitis C virus (HCV)

1 (11%)

 Non-HBV, non-HCV

3 (33%)

BCLC staging

 

 B

1 (11%)

 C

8 (89%)

Number of liver tumor(s)

 Single

6 (67%)

 Multiple

3 (33%)

Portal vein thrombosis

 Present

3 (33%)

 Absent

6 (67%)

Regional lymph node metastasis

 Present

0 (0%)

 Absent

9 (100%)

Distant metastasis

 Present

1 (11%)

 Absent

8 (89%)

Maximum diameter of liver tumor, cm, median (range)

6.6 (2.3–12.3)

RT doses, Gy, median (range)

45 (37.5–53)