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Table 4 Complications regarding surgical spacer placement and particle radiotherapy

From: Surgical spacer placement for proton radiotherapy in locally advanced pancreatic body and tail cancers: initial clinical results

  No. of patients
(n = 9)
None, n (%) 2 (22.2)
Early period complicationsa
 Leukopenia
  Grade 1–2 0 (0)
  Grade 3–4 2 (22.2)
 Thrombocytopenia
  Grade 1–2 1 (11.1)
  Grade 3–4 0 (0)
 Dermatitis
  Grade 1–2 4 (44.4)
  Grade 3–4 0 (0)
 Abdominal pain
  Grade 1–2 3 (33.3)
  Grade 3–4 0 (0)
 Nausea
  Grade 1–2 3 (33.3)
  Grade 3–4 0 (0)
 Anorexia
  Grade 1–2 1 (11.1)
  Grade 3–4 1 (11.1)
Late period complicationsb
 Gastrointestinal ulcer
  Grade 1–2 2 (22.2)
  Grade 3–4 0 (0)
 Gastric perforation
  Grade 1–2 0 (0)
  Grade 3-4c 1 (11.1)
 Abdominal infection by surgical spacer
  Grade 1–2 0 (0)
  Grade 3–4 0 (0)
  1. aEarly period complications: adverse event during the period from operation of surgical spacer placement to end of particle radiotherapy
  2. bLate period complications: adverse event during follow-up period after particle radiotherapy
  3. cGastric perforation occurred more than 4 months after particle radiotherapy