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Table 2 OAR constraints under MKM obtained from the conversion curve

From: RBE-weighted dose conversions for patients with recurrent nasopharyngeal carcinoma receiving carbon-ion radiotherapy from the local effect model to the microdosimetric kinetic model

OAR constraints/Gy (RBE)

LEM constraint (21 fractions)

LEM constraint (16 fractions)

MKM constraint (16 fractions)

70% NIRS constraints

Conversion factor

Brain stem Dmax

45.00

43.68

30.72 (30.71–30.73)

28.00

1.42 (1.40–1.44)

Spinal cord Dmax

30.00

29.28

16.64 (16.63–16.65)

21.00

1.76 (1.74–1.78)

Optic nerve D20

30.00

29.28

16.64 (16.63–16.65)

19.60

1.76 (1.74–1.78)