Table 3 Clinical histories of all three patients with Fazekas scores of 6
Patient number | Age | WMH volume (cm3) | ∆ MoCA score: baseline versus worst follow-up score | Outcome |
|---|---|---|---|---|
1 | 72 | 41.2 | 8-Point decrease at 6Â months | Somnolence for several months after WBRT with short-term memory and concentration impairment requiring full-time nursing support. An MRI 6Â months after treatment showed control of brain metastases and worsening leukoencephalopathy. Lived for 18Â months after WBRT |
2 | 83 | 43.6 | Did not complete a follow-up MoCA test | Admitted to nursing home with confusion 2Â months after WBRT. Did not attend any follow-up clinical trial appointments. An MRI 1Â year after treatment showed control of brain metastases and new leukoencephalopathy. Lived for 28Â months after WBRT in a nursing home |
3 | 71 | 66.3 | Did not complete a follow-up MoCA test | Three-month MRI showed control of brain metastases, but she did not attend the 3-month clinical trial appointment because she was sleeping 23Â h per day, compatible with somnolence syndrome. Lived for 6Â months after WBRT in a hospice |