Table 1 Characteristics of 252 patients with locoregional recurrent ESCC at initial treatment
Variables | Number | Percent |
|---|---|---|
Age (years) | ||
> 60 | 126 | 50.0 |
≤ 60 | 126 | 50.0 |
Gender | ||
Male | 206 | 81.7 |
Female | 46 | 18.3 |
Smoking | ||
Yes | 122 | 48.4 |
No | 130 | 51.6 |
Alcohol consumption | ||
Yes | 108 | 42.9 |
No | 144 | 57.1 |
Family history of malignancy | ||
Yes | 45 | 17.9 |
No | 207 | 82.1 |
Primary tumor location | ||
Upper thoracic | 72 | 28.6 |
Middle and lower thoracic | 180 | 71.4 |
Length (cm) | ||
≤ 4 | 152 | 60.3 |
4 < to ≤ 6 | 71 | 28.2 |
> 6 | 29 | 11.5 |
Macroscopic tumor type | ||
Medullary | 134 | 53.2 |
Ulcerative | 83 | 32.9 |
Constrictive | 15 | 6.0 |
Mushroom | 20 | 7.9 |
Tumor differentiation | ||
Higher | 36 | 14.3 |
Middle | 143 | 56.7 |
Lower | 73 | 29.0 |
T stage | ||
T1–T2 | 79 | 31.3 |
T3–T4 | 173 | 68.7 |
N stage | ||
N0 | 110 | 43.7 |
N1 | 111 | 44.0 |
N2 | 31 | 12.3 |
Initial clinical/pathological stage | ||
I–II | 117 | 46.4 |
III–Iva | 135 | 53.6 |
Radiation dose (Gy) | ||
≤ 50 | 64 | 25.4 |
> 50 | 188 | 74.6 |
Daily dose (Gy) | ||
1.8 | 61 | 24.2 |
2.0 | 180 | 71.4 |
> 2.0 | 11 | 4.4 |
Initial treatment | ||
CRT | 167 | 66.3 |
Surgery + CRT | 85 | 33.7 |
Radiotherapy technique | ||
Conventional treatment | 20 | 7.9 |
3D-CRT | 113 | 44.9 |
IMRT | 119 | 47.2 |