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Table 1 Baseline characteristics

From: Long-term outcomes of moderately hypofractionated radiotherapy (67.5 Gy in 25 fractions) for prostate cancer confined to the pelvis: a single center retrospective analysis

Characteristic

Number of patients (%)

Age (years)

 Median (range)

71 (51–87)

Gleason score

 ≤ 6

55 (22.4)

 7

96 (39.0)

 8

51 (20.7)

 9

37 (15.0)

 10

7 (2.8)

PSA before treatment (ng/ml)

 Median (range)

31.8 (1.14–2376)

 ≤ 10

35 (14.2)

 10–20

53 (21.5)

 > 20

158 (64.2)

Clinical T stage

 T1

15 (6.1)

 T2

125 (50.8)

 T3

82 (33.3)

 T4

24 (9.8)

NCCN risk group

 Low risk

6 (2.4)

 Intermediate risk

49 (19.9)

 High risk

100 (40.7)

 Locally advanceda

49 (19.9)

 N1b

42 (17.1)

ADT duration (months)

 Median (range)

31 (1–154)

 ≤ 6 months

22 (8.9)

 > 6 and ≤ 12 months

30 (12.2)

 > 12 and ≤ 24 months

49 (19.7)

 > 24 and ≤ 36 months

81 (32.9)

 > 36 months

58 (23.6)

Irradiation field

 Prostate + seminal vesicles

110 (44.7)

 Prostate + seminal vesicles + pelvic lymph node

103 (41.9)

 Prostate + seminal vesicles + pelvic lymph node + residual pelvic lymph node boost

33 (13.4)

Pelvic lymph node boost dose

 60 Gy/2.4 Gy/25f

10 (4.0)

 62.5 Gy/2.5 Gy/25f

2 (0.8)

 65 Gy/2.6 Gy/25f

2 (0.8)

 67.5 Gy/2.7 Gy/25f

19 (7.7)

  1. ADT androgen deprivation therapy, PSA prostate-specific antigen, NCCN National Comprehensive Cancer Network, EBRT external beam radiation therapy
  2. aLocally advanced = T3b–T4
  3. bN1 is defined as lymph nodes within pelvis with minimum diameter ≥ 1 cm detected on CT or MRI at initial diagnosis