Table 4 Acute toxicities in the 394 NPC patients
Acute toxicity | NTZ group N = 50 (%) | Non-NTZ group N = 344 (%) | P value |
|---|---|---|---|
Leukopenia | 0.739 | ||
G0–G1 | 18 (36.00) | 129 (37.50) | |
G2 | 14 (28.00) | 100 (29.07) | |
G3 | 14 (28.00) | 91 (26.45) | |
G4 | 4 (8.00) | 24 (6.98) | |
Neutropenia | 0.947 | ||
G0–G1 | 26 (52.00) | 173 (50.29) | |
G2 | 13 (26.00) | 98 (28.49) | |
G3 | 10 (20.00) | 73 (21.22) | |
G4 | 1 (2.00) | 0 | |
Anemia | 0.811 | ||
G0–G1 | 40 (80.00) | 279 (81.10) | |
G2 | 7 (14.00) | 51 (14.83) | |
G3 | 3 (6.00) | 14 (4.07) | |
Thrombocytopenia | 0.650 | ||
G0–G1 | 45 (90.00) | 316 (91.86) | |
G2 | 4 (8.00) | 24 (6.98) | |
G3 | 1 (2.00) | 4 (1.17) | |
Hepatotoxicity | 0.760 | ||
G0–G1 | 43 (86.00) | 290 (84.30) | |
G2 | 5 (10.00) | 39 (11.34) | |
G3 | 2 (4.00) | 15 (4.36) | |
Nephrotoxicity | 0.671 | ||
G0–G1 | 47 (94.00) | 318 (92.44) | |
G2 | 3 (6.00) | 19 (5.52) | |
G3 | 0 | 7 (2.03) | |
Skin reaction | 0.866 | ||
G0–G1 | 37 (74.00) | 257 (74.71) | |
G2 | 11 (22.00) | 79 (22.97) | |
G3 | 2 (4.00) | 8 (2.33) | |
Mucositis | 0.594 | ||
G0–G1 | 16 (32.00) | 117 (34.01) | |
G2 | 19 (38.00) | 139 (40.41) | |
G3 | 13 (26.00) | 76 (22.09) | |
G4 | 2 (4.00) | 12 (3.49) | |
Nausea | 0.895 | ||
G0–G1 | 27 (54.00) | 178 (51.74) | |
G2 | 17 (34.00) | 130 (37.79) | |
G3 | 4 (8.00) | 31 (9.01) | |
G4 | 2 (4.00) | 5 (1.45) | |
Vomiting | 0.803 | ||
G0–G1 | 35 (70.00) | 233 (67.73) | |
G2 | 9 (18.00) | 72 (20.93) | |
G3 | 6 (12.00) | 39 (11.34) | |
Diarrhea | 0.693 | ||
G0–G1 | 44 (88.00) | 309 (89.83) | |
G2 | 6 (12.00) | 35 (10.17) | |
Weight loss | 0.623 | ||
G0–G1 | 38 (76.00) | 271 (78.78) | |
G2 | 10 (20.00) | 65 (18.90) | |
G3 | 2 (4.00) | 8 (2.33) | |