Table 3 Multivariate logistic regression analysis to assess endoscopic factors affecting the duration of best response
Endoscopic findings | Early responder (n = 35) | Delayed responder (n = 8) | P-valuea |
|---|---|---|---|
Tumor location on endoscopy | 0.728 | ||
Fundus, cardina (n = 6) | 4 (11.4) | 2 (25.0) | |
Body (n = 18) | 16 (45.7) | 2 (25.0) | |
Antrum, pylorus (n = 4) | 3 (8.6) | 1 (12.5) | |
Duodenal 2nd portion (n = 5) | 4 (11.4) | 1 (12.5) | |
Duodenal 3rd portion (n = 2) | 1 (2.9) | 1 (12.5) | |
Multi-section in single organ (n = 8) | 7 (20.0) | 1 (12.5) | |
Initial size on endoscopy ≥2 cm | 0.370 | ||
< 2 cm (n = 8) | 7 (20.0) | 1 (12.5) | |
≥ 2 cm (n = 14) | 10 (28.6) | 4 (50.0) | |
N/A (n = 21) | 18 (51.4) | 3 (37.5) | |
Multiplicity | 0.967 | ||
Single (n = 11) | 9 (25.7) | 2 (25.0) | |
Multiple (n = 32) | 26 (74.3) | 6 (75.0) | |
Endoscopic pattern | 0.594 | ||
Erythema (n = 4) | 4 (11.4) | 0 | |
Erosion (n = 1) | 1 (2.9) | 0 | |
Nodularity (n = 20) | 15 (42.9) | 5 (62.5) | |
Ulceration (n = 10) | 8 (22.9) | 2 (25.0) | |
Atrophy (n = 8) | 7 (20.0) | 1 (12.5) | |
Depth on EUS | 0.083 | ||
Mucosa to MM (n = 9) | 9 (25.7) | 0 | |
SM (n = 15) | 11 (31.4) | 4 (50.0) | |
PM (n = 6) | 4 (11.4) | 2 (25.0) | |
N/A (n = 13) | 11 (31.4) | 2 (25.0) | |
Depth within the mucosal layerb | 0.027 | ||
Within the mucosal layer (n = 9) | 9 (37.5) | 0 | |
Beyond the mucosal layer (n = 21) | 15 (62.5) | 6 (100) |