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Table 5 Effect of stage and tumor kinetics on locoregional control and overall survival

From: Impact of delays in radiotherapy of head and neck cancer on outcome

Parameters

Locoregional control

Cause specific hazard

HR

95% CI

P-value

HR

95% CI

P-value

TNM stage

(IV vs. I-III)

2.73

0.57–13.18

0.210

2.46

0.82–7.41

0.110

VTU

(per cm3)

1.02

0.99–1.04

0.168

1.02

1.01–1.00

0.005

VTU relative increase rate

(per %/day)

0.99

0.89–1.09

0.811

0.97

0.88–1.06

0.465

VTU relative increase rate

(≤1% vs. > 1%/day)

1.52

0.31–7.31

0.603

1.48

0.49–4.47

0.483

  1. VTU Volume of primary tumor