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Table 5 Effect of stage and tumor kinetics on locoregional control and overall survival

From: Impact of delays in radiotherapy of head and neck cancer on outcome

Parameters Locoregional control Cause specific hazard
HR 95% CI P-value HR 95% CI P-value
TNM stage
(IV vs. I-III)
2.73 0.57–13.18 0.210 2.46 0.82–7.41 0.110
VTU
(per cm3)
1.02 0.99–1.04 0.168 1.02 1.01–1.00 0.005
VTU relative increase rate
(per %/day)
0.99 0.89–1.09 0.811 0.97 0.88–1.06 0.465
VTU relative increase rate
(≤1% vs. > 1%/day)
1.52 0.31–7.31 0.603 1.48 0.49–4.47 0.483
  1. VTU Volume of primary tumor