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Table 2 Univariate and multivariate analysis for local failure

From: Immune checkpoint inhibition in patients treated with stereotactic radiation for brain metastases

Covariate HR (95% CI) P-value
Univariate
Surgical resection 1.44 (0.44–4.75) 0.55
Tumor size ≤2 cm 0.36 (0.17–0.75) 0.01
Concurrent systemic therapy 1.37 (0.64–2.97) 0.42
Location of metastasis 1.10 (0.47–2.54) 0.83
Histology
 Renal cell 0.40 (0.04–3.55) 0.41
 Melanoma 0.34 (0.04–3.09) 0.22
 Squamous cell 1.67 (0.37–7.48) 0.50
 Adenocarcinoma 1.23 (0.42–3.56) 0.71
Recent Immunotherapy 0.18 (0.04–0.75) 0.02
Prior WBRT 1.88 (0.94–3.76) 0.08
Multivariate
Recent immunotherapy 0.26 (0.06–1.17) 0.08
Prior WBRT 1.66 (0.75–3.67) 0.21
Tumor size ≤2 cm 0.38 (0.17–0.84) 0.02