Table 2 Univariate and multivariate analysis for local failure
From: Immune checkpoint inhibition in patients treated with stereotactic radiation for brain metastases
Covariate | HR (95% CI) | P-value |
|---|---|---|
Univariate | ||
 Surgical resection | 1.44 (0.44–4.75) | 0.55 |
 Tumor size ≤2 cm | 0.36 (0.17–0.75) | 0.01 |
 Concurrent systemic therapy | 1.37 (0.64–2.97) | 0.42 |
 Location of metastasis | 1.10 (0.47–2.54) | 0.83 |
Histology | ||
 Renal cell | 0.40 (0.04–3.55) | 0.41 |
 Melanoma | 0.34 (0.04–3.09) | 0.22 |
 Squamous cell | 1.67 (0.37–7.48) | 0.50 |
 Adenocarcinoma | 1.23 (0.42–3.56) | 0.71 |
 Recent Immunotherapy | 0.18 (0.04–0.75) | 0.02 |
 Prior WBRT | 1.88 (0.94–3.76) | 0.08 |
Multivariate | ||
 Recent immunotherapy | 0.26 (0.06–1.17) | 0.08 |
 Prior WBRT | 1.66 (0.75–3.67) | 0.21 |
 Tumor size ≤2 cm | 0.38 (0.17–0.84) | 0.02 |