Dosimetric Parameters | SpaceOAR group (mean ± SD) | No-SpaceOAR group (mean ± SD) | p |
---|---|---|---|
Baseline Planning: | |||
Rectum | |||
V35Gy < 1 cc | 0.01 ± 0.02 | 0.07 ± 0.14 | 0.21 |
V32Gy < 5% | 0.73 ± 0.6 | 3.28 ± 0.9 | 0.001 |
V28Gy < 10% | 2.48 ± 1.73 | 7.88 ± 0.98 | 0.001 |
V18Gy < 35% | 15.99 ± 4.53 | 19.98 ± 2 | 0.039 |
Rectal Volume (cc) | 72.6 ± 39.8 | 46 ± 8 | 0.06 |
Bladder | |||
V35Gy < 1 cc | 0.09 ± 0.11 | 0.24 ± 0.21 | 0.04 |
V30Gy (%) | 7.09 ± 4.90 | 8.15 ± 3.42 | 0.24 |
V20Gy (%) | 17.19 ± 9.41 | 19.7 ± 6.74 | 0.21 |
V10Gy (%) | 36.25 ± 12.89 | 39.86 ± 11.35 | 0.43 |
V5Gy (%) | 46.98 ± 16.58 | 54.85 ± 16.22 | 0.21 |
Bladder Volume (cc) | 390.9 ± 182.8 | 255.6 ± 108.8 | 0.06 |
Urethra | |||
V35 Gy < 1 cc | 0.3 ± 0.31 | 0.33 ± 0.25 | 0.72 |
V33.2 Gy > 95% | 100 ± 0 | 99.94% ± 0.18% | 0.35 |
PTV | |||
PTV37.5Gy < 2% | 0.5 ± 0.62 | 0.74 ± 0.67 | 0.35 |
PTV33.2Gy > 95% | 98.55 ± 1.11 | 96.8% ± 1.25% | 0.036 |
PTV Volume (cc) | 121.8 ± 20.9 | 106.5 ± 27 | 0.17 |
Adaptive daily Planning: | |||
Rectum | |||
V35Gy < 1 cc | 0.01 ± 0.03 | 0.10 ± 0.16 | 0.0001 |
V32Gy < 5% | 0.88 ± 1 | 3.43 ± 1.33 | 0.00001 |
V28Gy < 10% | 2.95 ± 2.46 | 8.07 ± 1.61 | 0.00001 |
V18Gy < 35% | 14.97 ± 5.76 | 20.81 ± 2.59 | 0.00001 |
Rectal Volume (cc) | 49.7 ± 16.2 | 47.7 ± 10 | 0.16 |
Bladder | |||
V35Gy < 1 cc | 0.04 ± 0.09 | 0.25 ± 0.32 | 0.00004 |
V30Gy (%) | 6.98 ± 2.79 | 7.67 ± 5.86 | 0.43 |
V20Gy (%) | 18.75 ± 6.86 | 19.33 ± 10.41 | 0.78 |
V10Gy (%) | 40.06 ± 13.17 | 39.18 ± 14.85 | 0.70 |
V5Gy (%) | 52.97 ± 17.77 | 53.37 ± 19.97 | 0.83 |
Bladder Volume (cc) | 215.4 ± 166.9 | 217.5 ± 112.5 | 0.17 |
Urethra | |||
V35 Gy < 1 cc | 0.23 ± 0.20 | 0.22 ± 0.17 | 0.92 |
V33.2 Gy > 95% | 99.98 ± 0.13 | 100% ± 0% | 0.29 |
PTV | |||
PTV37.5Gy < 2% | 0.45 ± 0.51 | 1.39 ± 1.05 | 0.0001 |
PTV33.2Gy > 95% | 97.91 ± 1.35 | 95.96% ± 4.01% | 0.002 |
PTV Volume (cc) | 118.3 ± 40.1 | 111.4 ± 35.5 | 0.12 |