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Table 5 Baseline planning and daily adaptive treatment sessions dosimetric data in patients with and without spacer

From: Impact of hydrogel peri-rectal spacer insertion on prostate gland intra-fraction motion during 1.5 T MR-guided stereotactic body radiotherapy

Dosimetric Parameters

SpaceOAR group

(mean ± SD)

No-SpaceOAR group

(mean ± SD)

p

Baseline Planning:

 Rectum

  V35Gy < 1 cc

0.01 ± 0.02

0.07 ± 0.14

0.21

  V32Gy < 5%

0.73 ± 0.6

3.28 ± 0.9

0.001

  V28Gy < 10%

2.48 ± 1.73

7.88 ± 0.98

0.001

  V18Gy < 35%

15.99 ± 4.53

19.98 ± 2

0.039

  Rectal Volume (cc)

72.6 ± 39.8

46 ± 8

0.06

 Bladder

  V35Gy < 1 cc

0.09 ± 0.11

0.24 ± 0.21

0.04

  V30Gy (%)

7.09 ± 4.90

8.15 ± 3.42

0.24

  V20Gy (%)

17.19 ± 9.41

19.7 ± 6.74

0.21

  V10Gy (%)

36.25 ± 12.89

39.86 ± 11.35

0.43

  V5Gy (%)

46.98 ± 16.58

54.85 ± 16.22

0.21

  Bladder Volume (cc)

390.9 ± 182.8

255.6 ± 108.8

0.06

 Urethra

  V35 Gy < 1 cc

0.3 ± 0.31

0.33 ± 0.25

0.72

  V33.2 Gy > 95%

100 ± 0

99.94% ± 0.18%

0.35

 PTV

  PTV37.5Gy < 2%

0.5 ± 0.62

0.74 ± 0.67

0.35

  PTV33.2Gy > 95%

98.55 ± 1.11

96.8% ± 1.25%

0.036

  PTV Volume (cc)

121.8 ± 20.9

106.5 ± 27

0.17

Adaptive daily Planning:

 Rectum

  V35Gy < 1 cc

0.01 ± 0.03

0.10 ± 0.16

0.0001

  V32Gy < 5%

0.88 ± 1

3.43 ± 1.33

0.00001

  V28Gy < 10%

2.95 ± 2.46

8.07 ± 1.61

0.00001

  V18Gy < 35%

14.97 ± 5.76

20.81 ± 2.59

0.00001

  Rectal Volume (cc)

49.7 ± 16.2

47.7 ± 10

0.16

 Bladder

  V35Gy < 1 cc

0.04 ± 0.09

0.25 ± 0.32

0.00004

  V30Gy (%)

6.98 ± 2.79

7.67 ± 5.86

0.43

  V20Gy (%)

18.75 ± 6.86

19.33 ± 10.41

0.78

  V10Gy (%)

40.06 ± 13.17

39.18 ± 14.85

0.70

  V5Gy (%)

52.97 ± 17.77

53.37 ± 19.97

0.83

  Bladder Volume (cc)

215.4 ± 166.9

217.5 ± 112.5

0.17

 Urethra

  V35 Gy < 1 cc

0.23 ± 0.20

0.22 ± 0.17

0.92

  V33.2 Gy > 95%

99.98 ± 0.13

100% ± 0%

0.29

PTV

  PTV37.5Gy < 2%

0.45 ± 0.51

1.39 ± 1.05

0.0001

  PTV33.2Gy > 95%

97.91 ± 1.35

95.96% ± 4.01%

0.002

  PTV Volume (cc)

118.3 ± 40.1

111.4 ± 35.5

0.12