Table 2 Technical parameters of radiotherapy for lentigo maligna and lentigo maligna melanoma

Lazarevic [10]

Grenz or soft x-rays (10–30 kV)

42–120 Gy in 3–13 fx, 3–4 day intervals

15 mm

Lamoureux [11]

Superficial x-rays («contact therapy»), 30–150 kV

40 Gy in 10 fx, 2x/week; or 39 Gy in 13 fx, 3x/week

5–10 mm

Hedblad [12]

Grenz rays (10 kV)

100–160 Gy, in 6 fx, 2x/week

10 mm

Lee [13]

Superficial x-rays

50 Gy in 20 fx

n.a.

Zalaudek [14]

Grenz rays, 10 kV

120 Gy in 6 fx

at least 5 mm

Farshad [15]

Grenz rays (12 kV, 107 patients) or superficial X-rays (20 to 50 kV, 57 patients)

12 kV: 100–120 Gy, 10–12 fx, 2x/week; 20–50 kV: 42–54 Gy, 7–9 fx, 2x/week

7–10 mm

Schmid-Wendter [16]

Grenz rays (14.5 kV)

excision of the nodular part of LMM before RT

100 Gy, 10 fx, 5x/week

5–20 mm

Christie [17]

Superficial x-rays (100 kV)

44 Gy in 11 daily fx or 57.5 Gy in 23 daily fx

at least 10 mm

Tsang [18]

Superficial/ orthovoltage x-rays (100–250 kV)

35 Gy in 5 daily fx, 45 Gy in 10 daily fx or 50 Gy in 15 daily fractions

5–10 mm

Harwood [19]

Superficial/orthovoltage x-rays (LM: 100 kV; LMM: 125–175 kV)

35 Gy in 5 daily fx, 45 Gy in 10 daily fx, 50 Gy in 10–20 daily fx

at least 10 mm

Richter [20]

LM: Grenz rays (9 kV) or superficial x-rays (48.5 kV)

LMM: superficial x-rays (26–38 kV)

LM: 10,000 R in 5–10 fx

LMM: 6000–10,000 R in 12–20 fx

n.a.

Kopf [21]

Grenz rays (12 kV)

10,000 R in 5 fx, 3–4 day intervals

5 mm

Braun-Falco [22]

Grenz rays (14.5 kV)

10,000 R in 5–10 daily fx

n.a.

Arma-Szlachcic [23]

LM: Grenz rays (12 kV); LMM: Grenz rays or superficial x-rays (50–60 kV)

LM: most commonly 10,000–12,000 R in 5–6 fx every 5–7 days; LMM: various schedules

n.a.