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Table 4 Means and standard deviations of dose volume histogram (DVH) metrics in target and normal organs over 13 patients. All plans were renormalized based on GTV median dose D50

From: On the pitfalls of PTV in lung SBRT using type-B dose engine: an analysis of PTV and worst case scenario concepts for treatment plan optimization

 

PTVITV(i)

PTVVH(ii)

WCSCITV(iii)

WCSGTV(iv)

p-value < 0.05

GTV

D98 (Gy)

50.3 ± 0.6 (48.7–51.0)

51.3 ± 1.0 (49.1–52.4)

50.0 ± 1.4 (47.9–52.5)

49.8 ± 1.2 (46.4–51)

(ii)-(iv)

D50 (Gy)

54.1 ± 0.2 (53.8–54.5)

54.0 ± 0.0 (54.0–54.0)

54.1 ± 0.3 (53.5–54.6)

54.0 ± 0.0 (54.0–54.0)

 

D2 (Gy)

56.7 ± 0.9 (55.1–58.8)

56.0 ± 0.9 (55.1–57.7)

57.0 ± 1.1 (55.0–58.9)

56.8 ± 0.7 (55.8–58.4)

(ii)-(iii)

Chest Wall

V30Gy (cm3)

8.2 ± 7.9 (0.0–24.5)

8.1 ± 6.4 (0.0–18.8)

6.7 ± 4.8 (0.0–15.0)

6.6 ± 4.8 (0.0–15.4)

 

Lung

V5Gy (cm3)

17.1 ± 5.3 (2.6–13.6)

17.9 ± 4.3 (2.9–11.7)

17.4 ± 5.1 (2.6–11.9)

16.7 ± 5.1 (2.4–12.3)

(ii)-(iv)

V20Gy (cm3)

6.6 ± 3.3 (7.7–30.0)

6.7 ± 3.0 (8.0–26.8)

6.2 ± 3.0 (7.4–28.7)

6.1 ± 3.1 (7.1–28.4)

(ii)-(iii); (ii)-(iv)

MLD (Gy)

3.9 ± 1.6 (1.8–7.2)

4.0 ± 1.3 (1.9–6.1)

3.9 ± 1.4 (1.8–6.3)

3.7 ± 1.3 (1.7–6.4)

(ii)-(iv)

  1. Abbreviations are the same as in Table 1