Fig. 5
a From left to right: HU and dose profile of a proton spread-out Bragg peak (SOBP) for a beam entering via the frontal sinus. SOBP dose and dose difference distribution in a 2D sagittal plane as planned on the sCT and then delivered on the CT using a prescribed dose of 2 Gy. Adapted from [48]. b Original MRI, CT and pseudoCTs generated with a 2D and a 3D Unet for an exemplary brain case. The SFUD proton dose distribution for a single gantry angle is depicted on the original CT and the two pseudoCTs. The generic target volume is marked in red, the 95% iso-dose line in green. Adapted from [49]