Table 1 Multivariable logistic analysis of the predictor of immunotherapy in PDAC patients who received definitive surgery of the pancreatic tumor
Variable | Immunotherapy 636 (1.01%) | No Immunotherapy 62,518 (98.99%) | Total 63,154 | Odds Ratio | 95% CI | P | |
|---|---|---|---|---|---|---|---|
Age at diagnosis, Median (range) | 62.00 (29–90) | 67.00 (18–90) | 63,154 | 0.973 | 0.965–0.981 | < 0.0001 | |
Sex | Male | 352 (55.35) | 31,719 (50.74) | 32,071 (50.78) | 1 | Reference | Â |
Female | 284 (44.65) | 30,799 (49.26) | 31,083 (49.22) | 0.844 | 0.715–0.997 | 0.046 | |
Race | White | 574 (92.13) | 53,761 (86.84) | 54,335 (86.89) | 1 | Reference | Â |
Black | 28 (4.49) | 5982 (9.66) | 6010 (9.61) | 0.479 | 0.323–0.710 | 0.0003 | |
Other | 21 (3.37) | 21,68 (3.50) | 2189 (3.50) | 0.787 | 0.483–1.283 | 0.338 | |
Unknown | 13 | 607 | 620 | Â | Â | Â | |
Education | > = 13% HG | 167 (26.47) | 24,941 (40.05) | 25,108 (39.91) | 0.649 | 0.538–0.784 | 0.0001 |
< 13% | 464 (73.53) | 37,336 (59.95) | 37,800 (60.09) | 1 | Reference |  | |
Unknown | 5 | 241 | 246 | Â | Â | Â | |
Income | > = $35,000 | 459 (72.74) | 38,308 (61.54) | 38,767 (61.65) | 1 | Reference |  |
< 35,000 | 172 (27.26) | 23,944 (38.46) | 24,116 (38.35) |  | NS | 0.160 | |
Unknown | 5 | 266 | 271 | Â | Â | Â | |
Place of Living | Urban | 604 (99.02) | 59,667 (98.11) | 60,271 (98.12) | 1 | Reference | Â |
Rural | 6 (0.98) | 1150 (1.89) | 1156 (1.88) | 0.414 | 0.154–1.114 | 0.081 | |
Unknown | 26 | 1701 | 1727 | Â | Â | Â | |
Hospital Type | Academic | 505 (80.41) | 34,074 (55.04) | 34,579 (55.30) | 1 | Reference | Â |
Community | 123 (19.59) | 27,831 (44.96) | 27,954 (44.70) | 0.261 | 0.212–0.322 | 0.0001 | |
Unknown | 8 | 613 | 621 | Â | Â | Â | |
Insurance Status | Insured | 623 (98.89) | 60,145 (97.73) | 60,768 (97.74) | 1 | Reference | Â |
Not insured | 7 (1.11) | 1399 (2.27) | 1406 (2.26) | 0.503 | 0.237–1.069 | 0.074 | |
Unknown | 6 | 974 | 980 | Â | Â | Â | |
Charlson/Deyo Score | 0 | 486 (76.42) | 40,852 (65.34) | 41,338 (65.46) | 1 | Reference | Â |
1 | 125 (19.65) | 16,270 (26.02) | 16,395 (25.96) | 0.728 | 0.591–0.896 | 0.003 | |
> = 2 | 25 (3.93) | 5396 (8.63) | 5421 (8.58) | 0.519 | 0.340–0.792 | 0.002 | |
Chemotherapy | Yes | 608 (95.60) | 42,622 (68.18) | 43,230 (68.65) | 1 | Reference | Â |
No | 28 (4.40) | 19,896 (31.82) | 19,924 (31.55) | 0.209 | 0.138–0.316 | 0.0001 | |
Radiation Therapy | Yes | 459 (72.17) | 22,068 (35.30) | 22,527 (35.67) | 1 | Reference | Â |
No | 177 (27.83) | 40,450 (64.70) | 40,627 (64.33) | 0.350 | 0.289–0.425 | < 0.0001 | |
Year of Diagnosis | 2004–2010 | 330 (51.89) | 27,978 (44.75) | 28,308 (44.82) | 1.268 | 1.073–1.499 | < 0.005 |
2011–2016 | 306 (48.11.) | 34,540 (55.25) | 34,846 (55.18) | 1 | Reference |  | |