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Table 5 Univariate and Multivariate Cox analyses of treatment methods for OS after PSM

From: Effect of neoadjuvant radiotherapy on survival of non-metastatic pancreatic ductal adenocarcinoma: a SEER database analysis

  

Before PSM

After PSM

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

TNM stage

Treatment

P

HR

95%CI

P

P

HR

95%CI

P

T1-3N0M0

< 0.001

  

0.038

0.048

  

0.176

Only surgery

 

Reference

Reference

Reference

 

Reference

Reference

Reference

Neoadjuvant radiotherapy

1.486

1.315–1.679

0.038

 

1.164

0.934–1.449

0.176

T1-3N0M0

0.016

  

0.006

0.039

  

0.125

Neoadjuvant radiotherapy

 

Reference

Reference

Reference

 

Reference

Reference

Reference

Adjuvant radiotherapy

0.809

0.695–0.941

0.006

 

0.807

0.649–1.035

0.125

T1-3N0M0

0.001

  

0.001

0.034

  

0.025

Surgery plus chemotherapy

 

Reference

Reference

Reference

 

Reference

Reference

Reference

Neoadjuvant radiotherapy

1.285

1.107–1.491

0.001

 

1.280

1.045–1.574

0.025

T1-3N + M0

0.002

  

0.008

0.049

  

0.036

Only surgery

 

Reference

Reference

Reference

 

Reference

Reference

Reference

Neoadjuvant radiotherapy

0.795

0.671–0.942

0.008

 

0.618

0.429–0.863

0.036

T1-3N + M0

0.019

  

0.015

0.040

  

0.022

Adjuvant radiotherapy

 

Reference

Reference

Reference

 

Reference

Reference

Reference

Neoadjuvant radiotherapy

1.047

1.013–1.706

0.015

 

1.364

1.046–1.777

0.022

T1-3N + M0

0.035

  

0.795

0.021

  

0.541

Surgery plus chemotherapy

 

Reference

Reference

Reference

 

Reference

Reference

Reference

Neoadjuvant radiotherapy

1.023

0.863–1.212

0.795

 

1.083

0.838–1.400

0.541

T4NxM0

< 0.001

  

< 0.001

< 0.001

  

< 0.001

Only surgery

 

Reference

Reference

Reference

 

Reference

Reference

Reference

Neoadjuvant radiotherapy

0.459

0.349–0.602

< 0.001

 

0.466

0.331–0.657

< 0.001

T4NxM0

< 0.001

  

< 0.001

0.002

  

0.002

Adjuvant radiotherapy

 

Reference

Reference

Reference

 

Reference

Reference

Reference

Neoadjuvant radiotherapy

0.590

0.445–0.781

< 0.001

 

0.589

0.419–0.830

0.002

T4NxM0

< 0.001

  

0.040

0.028

  

0.028

Surgery plus chemotherapy

 

Reference

Reference

Reference

 

Reference

Reference

Reference

Neoadjuvant radiotherapy

0.752

0.573–0.987

0.040

 

0.707

0.519–0.963

0.028

  1. PSM Propensity score matching, OS Overall Survival, CI Confidence intervals, HR Hazard ratios
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Radiation Oncology

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