Table 1 Patient and treatment characteristics
n = 110 patients | Median / n (% / range) |
|---|---|
Age | 59.4 (25–82) |
Sex | |
 Male | 64 (58.2) |
 Female | 44 (44.0) |
ECOG | |
 0 | 77 (70.0) |
 1 | 26 (23.6) |
 2 | 6 (5.5) |
 3 | 1 (0.9) |
Number of brain metastases | median: 2 (1–30) |
 1 | 47 (42.7) |
 2–4 | 53 (48.1) |
 > 4 | 10 (9.0) |
BRAF status | |
 positive | 57 (48.2) |
 negative/unknown | 46 (41.8) / 7 (6.3) |
extracranial metastases | |
 yes | 83 (75.5) |
 no | 27 (24.5) |
volume of brain metastases | |
 ≥ 1.5 cc | 55 (50.0) 1.5–24.54 cc |
 < 1.5 cc | 55 (50.0) 0.05–1.4 cc |
RT regimen | |
 SRS | 95 (86.4) |
 SRT | 15 (13.6) |
Concomitant systemic therapy | |
 IT | 67 (60.9) |
 TT | 34 (30.9) |
 combination | 9 (8.2) |