Fig. 3

a-d shows different pathological findings of neoadjuvant therapy. HE staining of TRG0–3 grade (AJCC standard), respectively (h&e, original magnification = ×20, Bar scale = 100 μm), the arrows indicate residual tumor cells. a It shows TRG0 (pCR) complete remission without residual tumor cells; b. It displays TRG1 with only a single or few residual tumor cells; c. It shows less response to tumors with residual tumor cells; d. It shows TRG3 poor response to tumors, in which few or no tumor cells were killed. Arrows shows tumor cells