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Table 1 Baseline clinical profiles of the 49 patients with radiation-induced choanal stenosis

From: Dosimetric parameters predict radiation-induced choanal stenosis in patients with nasopharyngeal carcinoma

Characteristic

Value

Age at diagnosis (range) / years old

44 (20–71)

No. of patients by gender

 Male

33 (67.3%)

 Female

16 (32.7%)

No. of patients by T stage

 T4

11 (22.4%)

 T3

29 (59.2%)

 T2

7 (14.3%)

 T1

2 (4.1%)

No. of patients by N stage

 N3

5 (10.2%)

 N2

26 (53.1%)

 N1

18 (36.7%)

 N0

0 (0.0%)

No. of patients by WHO pathologic subtypes

 I-II

0 (0.0%)

 III

100 (100.0%)

No. of patients by prior allergic rhinitis

 Yes

3 (6.1%)

 No

46 (93.9%)

No. of patients by chronic smokers

 Yes

9 (18.4%)

 No

40 (81.6%)

No. of patients by treatment modes

 RT

2 (4.1%)

 RT + CCT

12 (24.5%)

 NACT + RT + CCT

35 (71.4%)

Prescribed total dose (range) / Gy

70.00 (66.00–74.00)

Prescribed single dose (range) / Gy

2.19 (2.06–2.34)

Actual maximum GTV dose (range) / Gy

77.22 (73.77–83.50)

Actual minimum GTV dose (range) / Gy

69.79 (65.27–72.59)

Actual mean GTV dose (range) / Gy

73.75 (65.80–78.66)

No. of patients by RICS sides

 Right

24 (49.0%)

 Left

25 (51.0%)

SNOT-22 score (range)

17 (11–59)

  1. Abbreviations: WHO World Health Organization, RT radiotherapy, CCT concurrent chemotherapy, NACT neoadjuvant chemotherapy, GTV gross tumor volume, RICS radiation-induced choanal stenosis, SNOT-22 22-item sinonasal outcomes test