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Table 4 Joint prediction for HT

From: Thyroid V50 is a risk factor for hypothyroidism in patients with nasopharyngeal carcinoma treated with intensity-modulated radiation therapy: a retrospective study

Combined factors

HT

Z

P-value

No (%)

Yes (%)

Combined thyroid volume and thyroid V50

 Volume > 12.82 cm3 and V50 ≤ 24%

22 (70.97)

9 (29.03)

−5.45

< 0.001***

 Volume > 12.82 cm3 and V50 > 24%

62 (60.19)

41 (39.81)

  

 Volume ≤ 12.82 cm3 and V50 ≤ 24%

5 (50.00)

5 (50.00)

  

 Volume ≤ 12.82 cm3 and V50 > 24%

13 (20.97)

49 (79.03)

  

Combined N stage and thyroid V50

 N0–1 and V50 ≤ 24%

18 (85.71)

3 (14.29)

−2.86

< 0.01**

 N0–1 and V50 > 24%

24 (50.00)

24 (50.00)

  

 N2–3 and V50 ≤ 24%

9 (45.00)

11 (55.00)

  

 N2–3 and V50 > 24%

51 (43.59)

66 (56.41)

  

Combined thyroid volume and N stage

 Volume > 12.82 cm3 and N0–1

33 (68.75)

15 (31.25)

−5.50

< 0.001***

 Volume > 12.82 cm3 and N2–3

51 (59.30)

35 (40.70)

  

 Volume ≤ 12.82 cm3 and N0–1

9 (42.86)

12 (57.14)

  

 Volume ≤ 12.82 cm3 and N2–3

9 (17.65)

42 (82.35)

  
  1. **P < 0.01, ***P < 0.001