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Table 1 Dose criteria of RTOG 0933 protocol. Dose prescription of 30 Gy in 10 fractions

From: Volumetric modulated arc therapy (VMAT) for hippocampal-avoidance whole brain radiation therapy: planning comparison with Dual-arc and Split-arc partial-field techniques

RTOG 0933 protocolPer protocolAcceptable variationUnacceptable deviation
Whole brain PTVD2% < 37.5 GyD2% = 37.5 GyD2% > 40 Gy
D98% > 25 GyD98% < 25 GyV30 < 90%
HippocampusD100% < 9 GyD100% = 10 GyD100% > 10 Gy
Dmax < 16 GyDmax = 17 GyDmax > 17 Gy
Optic nerves and optic chiasmDmax < 37.5 GyDmax = 37.5 GyDmax > 37.5 Gy