Impact of genetic variant of HIPK2 on the risk of severe radiation pneumonitis in lung cancer patients treated with radiation therapy

Table 3 Association between genotypes and Grade ≥ 2 RP

Polymorphism and Genotype	No.of event	No.of total	Univariable analysis			Multivariable analysis
Polymorphism and Genotype	No.of event	No.of total	HR	95% CL	P	HR	95% CL	P
HIPK2: rs2030712
CT	14	35	1			1
CC	85	134	2.009	1.140–3.539	0.016	2.146	1.215–3.791	0.009

NOTE: Multiple analyses in this table were adjusted for all the factors listed in Table 1
Abbreviations: HR hazard ratio; CI confidence interval
Pc: P-value corrected by Benjamini and Hochberg False Discovery Rate correction

ISSN: 1748-717X