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Table 3 Correlations of CD8+ TILs density and clinicopathologic characteristics

From: Prognostic value of PD-L1 expression on tumor cells combined with CD8+ TIL density in patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy

  high, n (%) low, n (%) p-value
Age
  ≤ 65 years 12 (80) 3 (20)  
  > 65 years 6 (46) 7 (54) 0.403
Gender
 Female 14 (61) 9 (39)  
 Male 4 (80) 1 (20) 0.384
Karnofsky performance status
  > 80% 9 (90) 1 (10)  
  ≤ 80% 9 (50) 9 (50) 0.038
UICC stage
 III 17 (65) 9 (35)  
 IV 1 (50) 1 (50) 0.409
T category
 1–2 3 (60) 2 (40)  
 3–4 15 (65) 8 (35) 0.751
N category
 0–1 2 (67) 1 (33)  
 2–3 16 (64) 9 (36) 0.899
Histology
 Squamous cell carcinoma 8 (62) 5 (39)  
 Non- Squamous cell carcinoma 10 (67) 5 (33) 0.681
Tobacco consumption (PY)
 0 6 (75) 2 (25)  
 20–40 5 (71) 2 (29)  
  > 40 7 (54) 6 (46) 0.11
Grading
 Moderately differentiated 0 (0) 2 (100)  
 Poorly differentiated 16 (67) 8 (33)  
 anaplastic 2 (100) 0 (0) 0.067
PD-L1 expression
 0% 7 (58) 5 (42)  
  ≥ 1% 10 (67) 5 (33) 0.02