Table 3 Correlations of CD8+ TILs density and clinicopathologic characteristics
high, n (%) | low, n (%) | p-value | |
|---|---|---|---|
Age | |||
≤ 65 years | 12 (80) | 3 (20) | |
> 65 years | 6 (46) | 7 (54) | 0.403 |
Gender | |||
Female | 14 (61) | 9 (39) | |
Male | 4 (80) | 1 (20) | 0.384 |
Karnofsky performance status | |||
> 80% | 9 (90) | 1 (10) | |
≤ 80% | 9 (50) | 9 (50) | 0.038 |
UICC stage | |||
III | 17 (65) | 9 (35) | |
IV | 1 (50) | 1 (50) | 0.409 |
T category | |||
1–2 | 3 (60) | 2 (40) | |
3–4 | 15 (65) | 8 (35) | 0.751 |
N category | |||
0–1 | 2 (67) | 1 (33) | |
2–3 | 16 (64) | 9 (36) | 0.899 |
Histology | |||
Squamous cell carcinoma | 8 (62) | 5 (39) | |
Non- Squamous cell carcinoma | 10 (67) | 5 (33) | 0.681 |
Tobacco consumption (PY) | |||
0 | 6 (75) | 2 (25) | |
20–40 | 5 (71) | 2 (29) | |
> 40 | 7 (54) | 6 (46) | 0.11 |
Grading | |||
Moderately differentiated | 0 (0) | 2 (100) | |
Poorly differentiated | 16 (67) | 8 (33) | |
anaplastic | 2 (100) | 0 (0) | 0.067 |
PD-L1 expression | |||
0% | 7 (58) | 5 (42) | |
≥ 1% | 10 (67) | 5 (33) | 0.02 |