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Fig. 1 | Radiation Oncology

Fig. 1

From: Is in vivo and ex vivo irradiation equally reliable for individual Radiosensitivity testing by three colour fluorescence in situ hybridization?

Fig. 1

3-color-Fluorescence in situ hybridization. Metaphase spreads of human blood lymphocytes with chromosomes # 1 (red), # 2 (green) and # 4 (yellow) stained with a chromosome specific probe. DNA was counterstained with DAPI (blue). (a) Normal metaphase spread in comparison to a metaphase spread with complex aberrations in almost every chromosome (CCR), in sum scored with 10 breaks per metaphase. (b) The yellow arrows indicate chromosomal breaks and aberrations. Individual background B/M rates for both cancer cohorts (c) as well as the breakage rates after ex vivo and in vivo IR

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