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Table 1 Half-maximal inhibitory concentration (IC50) values of isogenic cells to chemotherapeutics

From: Mechanisms of different response to ionizing irradiation in isogenic head and neck cancer cell lines

Cytotoxic drug (μg/mL)

FaDu

FaDu-RR

Fold-potentiationa

2A3

Fold-potentiationa

Cisplatin

0.16 ± 0.007

0.284 ± 0.02b

1.8

0.1 ± 0.03

0.7

Oxaliplatin

0.75 ± 0.15

1.12 ± 0.15c

1.5

0.41 ± 0.13

0.5

Bleomycin

551 ± 132

521 ± 18

0.9

249 ± 63

0.5

  1. aFold-potentiation compared to parental FaDu cell line. b significant difference compared to FaDu and 2A3 cells. c significant difference compared to 2A3. Values are AM ± SEM