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Table 2 Univariate analyses of the prognostic factors for survival

From: Evaluating the optimal re-irradiation dose for locally recurrent esophageal squamous cell carcinoma after definitive radiotherapy

Factor No. MST (months) 2-year OS(%) 95%CI P value
Age
 < 70 18 16 33.3 11.5–55.1 0.070
 ≥70 29 17 20.7 6.0–35.4  
Sex
 Male 35 16 20.0 6.7–33.3 0.083
 Female 12 17 41.7 13.9–69.5  
ECOG-PS
 0–1 24 18 37.5 18.1–56.9 0.014
 2–3 23 15 13.0 0.26–25.74  
Initial site
 Cervical +upper thoracic 20 17 30.0 10.0–50.0 0.100
 Middle thoracic 18 16 33.3 11.5–55.1  
 Lower thoracic 9 12 0  
Recurrence pattern
 Local 37 17 32.4 17.3–47.5 0.048
 Local +nodal 10 14 0  
Time to recurrence
 < 24 months 19 12 15.8 0.5–31.1 0.006
 ≥24 months 28 18 32.1 14.9–49.3  
Chemotherapy
 Yes 13 18 23.1 0.2–46.0 0.812
 No 34 16 26.5 11.6–41.4  
Re-RT dose
 <50Gy 15 11 0 < 0.001
 ≥50Gy 32 18 37.5 20.6–54.4  
  1. ECOG-PS Eastern Cooperative Oncology Group Performance Status, Re-RT re-irradiation, MST median survival time, OS overall survival, CI confidence interval