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Table 2 Univariate analyses of the prognostic factors for survival

From: Evaluating the optimal re-irradiation dose for locally recurrent esophageal squamous cell carcinoma after definitive radiotherapy

Factor

No.

MST (months)

2-year OS(%)

95%CI

P value

Age

 < 70

18

16

33.3

11.5–55.1

0.070

 ≥70

29

17

20.7

6.0–35.4

 

Sex

 Male

35

16

20.0

6.7–33.3

0.083

 Female

12

17

41.7

13.9–69.5

 

ECOG-PS

 0–1

24

18

37.5

18.1–56.9

0.014

 2–3

23

15

13.0

0.26–25.74

 

Initial site

 Cervical +upper thoracic

20

17

30.0

10.0–50.0

0.100

 Middle thoracic

18

16

33.3

11.5–55.1

 

 Lower thoracic

9

12

0

 

Recurrence pattern

 Local

37

17

32.4

17.3–47.5

0.048

 Local +nodal

10

14

0

 

Time to recurrence

 < 24 months

19

12

15.8

0.5–31.1

0.006

 ≥24 months

28

18

32.1

14.9–49.3

 

Chemotherapy

 Yes

13

18

23.1

0.2–46.0

0.812

 No

34

16

26.5

11.6–41.4

 

Re-RT dose

 <50Gy

15

11

0

< 0.001

 ≥50Gy

32

18

37.5

20.6–54.4

 
  1. ECOG-PS Eastern Cooperative Oncology Group Performance Status, Re-RT re-irradiation, MST median survival time, OS overall survival, CI confidence interval