Skip to main content

Table 1 Patient characteristics

From: Survival benefits of hypofractionated radiotherapy combined with temozolomide or temozolomide plus bevacizumab in elderly patients with glioblastoma aged ≥ 75 years

 

No. (%) of Patients

Age (yr)

 Median

80

 Range

75–87

Sex

 Male

19 (63.3)

 Female

11 (36.7)

Karnofsky performance status

 100, 90

2 (6.7)

 80, 70

17 (56.7)

 60, 50

11 (36.7)

Extent of resection

 Total resection

8 (26.7)

 Subtotal resection

3 (10)

 Partial resection

7 (23.3)

 Biopsy

12 (40)

Chemotherapy

 Temozolomide

20 (66.7)

 Temozolomide/Bevacizumab

10 (33.3)

Adjuvant Temozolomide cycles (n)

 Median

5

 Range

0–20

Use of corticosteroid

 Yes

6 (20)

 No

24 (80)

Treatment after tumor recurrence

 Best supportive care

21 (70)

 Bev

5 (16.7)

 Surgery followed by Temozolomide

1 (3.3)

 Temozolomide

1 (3.3)

 No recurrence

2 (6.7)

MGMT promoter status

 High

11 (36.7)

 Low

16 (53.3)

 N/A

3 (10)

IDH 1/2 status

 Wild-type

29 (96.7)

 Mutant

0

 N/A

1 (3.3)

  1. IDH Isocitrate dehydrogenase, MGMT O6-methylguanine DNA methyltransferase, N/A Not available