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Fig. 3 | Radiation Oncology

Fig. 3

From: Survival benefits of hypofractionated radiotherapy combined with temozolomide or temozolomide plus bevacizumab in elderly patients with glioblastoma aged ≥ 75 years

Fig. 3

Three representative patients whose T1-weighted magnetic resonance images with gadolinium enhancement showed a partial response. a An 80-year-old man presented with a left temporo-parietal enhanced tumor and underwent biopsy. b Afterwards, he received temozolomide combined with radiotherapy consisting of 45 Gy in 15 fractions and showed a remarkable response with cystic degeneration. c The tumor was MGMT promoter-hypomethylated. d A 78-year-old man presented with a left parietal enhanced tumor and underwent partial resection. e Afterwards, he received temozolomide combined with radiotherapy consisting of 45 Gy in 15 fractions and nearly achieved a complete response. f The tumor was MGMT promoter-hypermethylated. g A 77-year-old woman presented with a left temporal enhanced tumor and underwent partial resection. h Afterwards, she received temozolomide combined with radiotherapy consisting of 45 Gy in 15 fractions and achieved tumor size reduction. i The tumor was MGMT promoter-hypomethylated. Abbreviations: MGMT O-6-methylguanine DNA methyltransferase

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Radiation Oncology

ISSN: 1748-717X

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