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Table 2 Characteristic of all included patients

From: The prognosis benefits of adjuvant versus salvage radiotherapy for patients after radical prostatectomy with adverse pathological features: a systematic review and meta-analysis

ReferenceGroupAgeGleason score n, (≤6/7/≥8)Pathologic T stage (n)Preoperative PSA (ng/ml)Pre-RT PSA (ng/ml)PSM n (%)Radiation dose (Gy)
Briganti 2012ARTMedian (IQR):64 (60–68)160/185/45T3a:261 T3b:129Median(IQR): 10 (6.7–16.1)Median(IQR): 0 (0–0)245 (62.8)Median(IQR): 65 (60–70)
ESRTMedian (IQR):65 (61–69)163/173/54T3a:274 T3b:116Median(IQR): 10 (6.3–14.7)Median(IQR): 0.2 (0.1–0.3)238 (61.0)Median(IQR): 66 (66–66)
Buscariollo 2017ARTMedian (IQR):60 (54–65)31/83/56T2:43
T3:128
Median(IQR): 6 (5–10)< 0.1143 (83.6)Median(IQR): 61.2 (61.2, 64.8)
ESRTMedian (IQR):59 (54–63)43/142/45T2:90
T3:140
Median(IQR): 6 (5–10)Median(IQR): 0.3 (0.2–0.4)163 (70.9)Median(IQR): 64.8 (64.8, 64.8)
Fossati 2016ARTMedian (IQR):64 (61–69)57/120/66T3a:137 ≥ T3b:106Median(IQR): 9.3 (6.2–15.8)Median(IQR): 0 (0–0)181 (74)Median(IQR): 60 (60–65)
ESRTMedian (IQR):65 (60–70)49/147/71T3a:168 ≥ T3b:99Median(IQR): 9.8 (6.3–14.8)Median(IQR): 0.2 (0.1–0.3)138 (52)Median(IQR): 67 (66–67)
Hwang 2018ARTMedian (IQR):60 (55–65)50/210/106T2:98
T3:268
UC< 0.1313 (85.8)Median(IQR): 64.8 (61.2–66.0)
ESRTMedian (IQR):61 (54.6–65.3)33/209/124T2:109 T3:257UCMedian(IQR): 0.3 (0.2–0.4)318 (86.9)Median(IQR): 66.0 (64.8–70.0)
Borghetti 2017ARTOverall median (range): 65 (42–78)24/60/43T2:20 ≥ T3:107UCUC99 (78.0)UC
SRT42/57/32T2:50
≥T3:81
UCUC80 (61.1)UC
Hervas 2017ARTMean (range):62.7 (43.0–75.0)199(≤7)/20≤T2:83 ≥ T3:124UC≤0.5156 (70.9)UC
SRTMean (range):64.8 (42.0–82.0)393(≤7)/47≤T2:272 ≥ T3:172UCUC214 (47.5)UC
Mishra 2015ARTMedian:5912/40/19UCUCMedian:< 0.160 (81.1)Median:66
SRTMedian:6322/49/33UCUCMedian:0.686 (76.8)Median:66.6
Hsu 2015ARTUC14/34/26≤T2:12 ≥ T3:64UC< 0.150 (79)UC
SRTUC22/118/83≤T2:86 ≥ T3:143UCMedian(IQR): 0.5 (0.3–1.0)149 (86)UC
Tilki 2016ARTMedian (IQR):65 (60–70)0/116/97T2:9 T3:204Median(IQR): 12 (7.8–25.7)UC171 (80.3)range:60–70
SRTMedian (IQR):66 (61–70)1/340/163T2:63 T3:441Median(IQR): 11 (7.0–18.9)UC212 (42)range:60–70
Detti 2012ARTMean ± SD:65.1 ± 7.344/77/82T2:22
≥T3:181
Mean ± SD: 0.10 ± 0.28Mean ± SD: 0.47 ± 1.73101 (49.8)Mean ± SD: 66.2 ± 4.1
SRTMean ± SD:67.0 ± 6.025/26/53T2:23 ≥T3:81Mean ± SD: 0.85 ± 0.52Mean ± SD: 1.73 ± 3.1924 (23.1)Mean ± SD: 66.8 ± 4.1
Ost 2011ARTMedian(range):63 (51–77)64(including 3 + 4)/25(including 4 + 3)T2:21
≥T3:68
Median(range): 10.0 (3.0–47.9)< 0.268 (76)Median:74
SRTMedian(range):64 (42–75)64(including 3 + 4)/25(including 4 + 3)T2:21
≥T3:68
Median(range): 10.0 (3.5–148)≥0.259 (66)Median:76
Trabulsi 2008ARTMedian(range):62.0 (42–76)22/17/57≥T3:96Median(range): 8.3 (1.1–65.9)< 0.280 (83)Median(range): 60 (50–70)
SRTMedian(range):63.0 (47–75)22/17/57≥T3:96Median(range): 9.0 (1.7–39)Median(range): 0.7 (0.2–2)80 (83)Median(range): 64.8 (59–70)
Tsien 2003ARTMedian(range):63.0 (43.8–75.7)11/16/8≥T3:36Median(range): 11.6 (1.1–99.6)UC34 (89)Median(range): 64.0 (59.4–69.0)
SRTMedian(range):64.2 (42.1–78.6)17/27/8≥T3:38Median(range): 13.3 (0.2–120.0)Median(range): 1.2 (0.2–18.4)27 (47)Median(range): 65.0 (60.0–75.0)
Taylor 2003ARTmedian:609/35/30≤T2:27 ≥ T3:48Median:11Median:< 0.173 (96)Median(range): 60 (51–70)
SRTUC18/27/24≤T2:12 ≥ T3:59UCUCUCMedian(range): 70 (60–78)
Kalapurakal 2002ARTOverall median (range): 60 (48–78)Overall 66(≤7)/10UCOverall median(range):12.0 (4–82)UCoverall 40 (53)Median(range): 60 (60–65)
SRTUCMedian(range): 0.5 (0.2–6.5)Median(range): 65 (60–70)
  1. UC: unclear