Table 2 Characteristic of all included patients

Briganti 2012

ART

Median (IQR):64 (60–68)

160/185/45

T3a:261 T3b:129

Median(IQR): 10 (6.7–16.1)

Median(IQR): 0 (0–0)

245 (62.8)

Median(IQR): 65 (60–70)

ESRT

Median (IQR):65 (61–69)

163/173/54

T3a:274 T3b:116

Median(IQR): 10 (6.3–14.7)

Median(IQR): 0.2 (0.1–0.3)

238 (61.0)

Median(IQR): 66 (66–66)

Buscariollo 2017

ART

Median (IQR):60 (54–65)

31/83/56

T2:43

T3:128

Median(IQR): 6 (5–10)

< 0.1

143 (83.6)

Median(IQR): 61.2 (61.2, 64.8)

ESRT

Median (IQR):59 (54–63)

43/142/45

T2:90

T3:140

Median(IQR): 6 (5–10)

Median(IQR): 0.3 (0.2–0.4)

163 (70.9)

Median(IQR): 64.8 (64.8, 64.8)

Fossati 2016

ART

Median (IQR):64 (61–69)

57/120/66

T3a:137 ≥ T3b:106

Median(IQR): 9.3 (6.2–15.8)

Median(IQR): 0 (0–0)

181 (74)

Median(IQR): 60 (60–65)

ESRT

Median (IQR):65 (60–70)

49/147/71

T3a:168 ≥ T3b:99

Median(IQR): 9.8 (6.3–14.8)

Median(IQR): 0.2 (0.1–0.3)

138 (52)

Median(IQR): 67 (66–67)

Hwang 2018

ART

Median (IQR):60 (55–65)

50/210/106

T2:98

T3:268

UC

< 0.1

313 (85.8)

Median(IQR): 64.8 (61.2–66.0)

ESRT

Median (IQR):61 (54.6–65.3)

33/209/124

T2:109 T3:257

UC

Median(IQR): 0.3 (0.2–0.4)

318 (86.9)

Median(IQR): 66.0 (64.8–70.0)

Borghetti 2017

ART

Overall median (range): 65 (42–78)

24/60/43

T2:20 ≥ T3:107

UC

UC

99 (78.0)

UC

SRT

42/57/32

T2:50

≥T3:81

UC

UC

80 (61.1)

UC

Hervas 2017

ART

Mean (range):62.7 (43.0–75.0)

199(≤7)/20

≤T2:83 ≥ T3:124

UC

≤0.5

156 (70.9)

UC

SRT

Mean (range):64.8 (42.0–82.0)

393(≤7)/47

≤T2:272 ≥ T3:172

UC

UC

214 (47.5)

UC

Mishra 2015

ART

Median:59

12/40/19

UC

UC

Median:< 0.1

60 (81.1)

Median:66

SRT

Median:63

22/49/33

UC

UC

Median:0.6

86 (76.8)

Median:66.6

Hsu 2015

ART

UC

14/34/26

≤T2:12 ≥ T3:64

UC

< 0.1

50 (79)

UC

SRT

UC

22/118/83

≤T2:86 ≥ T3:143

UC

Median(IQR): 0.5 (0.3–1.0)

149 (86)

UC

Tilki 2016

ART

Median (IQR):65 (60–70)

0/116/97

T2:9 T3:204

Median(IQR): 12 (7.8–25.7)

UC

171 (80.3)

range:60–70

SRT

Median (IQR):66 (61–70)

1/340/163

T2:63 T3:441

Median(IQR): 11 (7.0–18.9)

UC

212 (42)

range:60–70

Detti 2012

ART

Mean ± SD:65.1 ± 7.3

44/77/82

T2:22

≥T3:181

Mean ± SD: 0.10 ± 0.28

Mean ± SD: 0.47 ± 1.73

101 (49.8)

Mean ± SD: 66.2 ± 4.1

SRT

Mean ± SD:67.0 ± 6.0

25/26/53

T2:23 ≥T3:81

Mean ± SD: 0.85 ± 0.52

Mean ± SD: 1.73 ± 3.19

24 (23.1)

Mean ± SD: 66.8 ± 4.1

Ost 2011

ART

Median(range):63 (51–77)

64(including 3 + 4)/25(including 4 + 3)

T2:21

≥T3:68

Median(range): 10.0 (3.0–47.9)

< 0.2

68 (76)

Median:74

SRT

Median(range):64 (42–75)

64(including 3 + 4)/25(including 4 + 3)

T2:21

≥T3:68

Median(range): 10.0 (3.5–148)

≥0.2

59 (66)

Median:76

Trabulsi 2008

ART

Median(range):62.0 (42–76)

22/17/57

≥T3:96

Median(range): 8.3 (1.1–65.9)

< 0.2

80 (83)

Median(range): 60 (50–70)

SRT

Median(range):63.0 (47–75)

22/17/57

≥T3:96

Median(range): 9.0 (1.7–39)

Median(range): 0.7 (0.2–2)

80 (83)

Median(range): 64.8 (59–70)

Tsien 2003

ART

Median(range):63.0 (43.8–75.7)

11/16/8

≥T3:36

Median(range): 11.6 (1.1–99.6)

UC

34 (89)

Median(range): 64.0 (59.4–69.0)

SRT

Median(range):64.2 (42.1–78.6)

17/27/8

≥T3:38

Median(range): 13.3 (0.2–120.0)

Median(range): 1.2 (0.2–18.4)

27 (47)

Median(range): 65.0 (60.0–75.0)

Taylor 2003

ART

median:60

9/35/30

≤T2:27 ≥ T3:48

Median:11

Median:< 0.1

73 (96)

Median(range): 60 (51–70)

SRT

UC

18/27/24

≤T2:12 ≥ T3:59

UC

UC

UC

Median(range): 70 (60–78)

Kalapurakal 2002

ART

Overall median (range): 60 (48–78)

Overall 66(≤7)/10

UC

Overall median(range):12.0 (4–82)

UC

overall 40 (53)

Median(range): 60 (60–65)

SRT

UC

Median(range): 0.5 (0.2–6.5)

Median(range): 65 (60–70)