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Table 4 Predictive value analysis of hemorrhoids and/or anal canal V20

From: Dose-volume analysis of predictors for acute anal toxicity after radiotherapy in prostate cancer patients

Groups Models AAT (cases) NAAT (cases) Sensitivity (%) Specificity(%) +PV
(%)
-PV
(%)
AUC
Training group
(N = 248 cases)
Model 1: Anal canal V20
 High(V20 > 74.93%) 53 45 54.01 70.00 54.08 70.00 0.620
 Low(V20 ≤ 74.93%) 45 105
Model 2: Hemorrhoid
 Yes 84 55 85.71 63.33 60.43 87.16 0.745
 No 14 95
Model 3:
 High V20 with hemorrhoid 46 13 46.94 91.33 77.97 72.49 0.691
 Others 52 137
Model 4:
 High V20 without hemorrhoid 7 32 7.14 78.67 17.95 56.46 0.429
 Others 91 118
Model 5:
 Low V20 with hemorrhoid 38 42 38.78 72.00 47.50 68.35 0.554
 Others 50 108
Model 6:
 Low V20 without hemorrhoid 7 63 7.14 58.00 10.00 48.88 0.326
 Others 91 87
Validation group
(N = 99 cases)
Model 1: Anal canal V20
 High(V20 > 74.93%) 18 13 58.06 80.88 58.06 80.88 0.665
 Low(V20 ≤ 74.93%) 13 55
Model 2: Hemorrhoid
 Yes 23 29 74.19 57.35 44.23 82.98 0.658
 No 8 39
Model 3:
 High V20 with hemorrhoid 11 4 35.48 94.12 75.00 76.19 0.631
 Others 20 64
Model 4:
 High V20 without hemorrhoid 7 9 22.58 86.76 43.75 71.08 0.534
 Others 24 59
Model 5:
 Low V20 with hemorrhoid 14 23 45.16 66.18 37.84 72.58 0.529
 Others 17 45
Model 6:
 Low V20 without hemorrhoid 2 29 6.45 57.35 6.45 57.35 0.306
 Others 29 39
  1. Abbreviations: V20 percentage of anal canal volume receiving more than 20 Gy; AAT acute anal toxicity; NAAT no-acute anal toxicity; +PV positive predictive value; −PV negative predictive value; AUC area under the curve