Impact of adaptive intensity-modulated radiotherapy on the neutrophil-to-lymphocyte ratio in patients with nasopharyngeal carcinoma

Table 2 Comparison of radiotherapy-related variables between the two groups

Characteristics	ART+IMRT(n = 50)	IMRT(n = 50)	P
Pre-NLR	2.00 ± 1.78	2.81 ± 2.54	0.076
Pre-CLC(10⁹/L)	1.54 ± 0.60	1.66 ± 0.76	0.381
Pre-CNC(10⁹/L)	4.12 ± 1.65	4.16 ± 1.87	0.907
Pre-CPC(10⁹/L)	222.9 ± 63.02	239.8 ± 59.93	0.155
Pre-HB(g/L)	143.26 ± 15.46	138.92 ± 44.15	0.534
ΔNLR(%)	−1.80 ± 114.02	70.34 ± 49.40	< 0.001^*
ΔCLC(%)	− 126.33 ± 119.97	−341.36 ± 320.99	< 0.001^*
ΔCNC(%)	−14.43 ± 65.43	−30.57 ± 89.83	0.288
ΔCPC(%)	−4.52 ± 23.15	−16.62 ± 32.07	0.036^*
ΔHCG(%)	45.68 ± 11.19	−45.7 ± 26.88	0.303
Δweight (Kg)	−3.76 ± 3.13	−5.04 ± 2.09	0.025^*
ΔWeight(%)	−7.99 ± 3.60	−5.98 ± 4.87	0.030^*
Acute radiation injury classification
Parotid glands			< 0.001^*
0	0	0
1	13	0
2	37	50
3	0	0
4	0	0
Skin			< 0.001^*
0	2	0
1	38	18
2	9	26
3	1	6
4	0	0
Oral			< 0.001^*
0	8	0
1	0	14
2	28	12
3	14	24
4	0	0

Abbreviations: NLR neutrophil-to-lymphocyte ratio, CLC circulating lymphocyte count, CPC circulating platelet count, CNC circulating neutrophil granulocyte count, HB the haemoglobin count
^*P ≤ 0.05

ISSN: 1748-717X