Table 3 Univariate logistic regression models for the risk of perineal wound complications
Variable | n (%) | OR (95%CI) | p | |
|---|---|---|---|---|
Absent (n = 148) | Present (n = 66) | |||
Gender | ||||
 Male | 102(68.9) | 49(74.2) | Ref |  |
 Female | 46(31.1) | 17(25.8) | 0.431(0.401–1.477) | 0.431 |
Age (years) | ||||
 < 45 | 18(12.2) | 9(13.7) | Ref |  |
 45–59 | 78(52.7) | 28(42.4) | 0.718(0.289–1.782) | 0.475 |
 ≥60 | 52(35.1) | 29(43.9) | 1.115(0.444–2.799) | 0.816 |
ECOG | ||||
 0 | 121(81.8) | 48(72.7) | Ref |  |
 1 | 27(18.2) | 18(27.3) | 1.681(0.848–3.330) | 0.137 |
BMI (kg/m2) | ||||
 < 18.5 | 4(2.7) | 3(4.5) | 1.781(0.377–8.417) | 0.466 |
 < 25 | 76(51.7) | 32(48.5) | Ref |  |
 ≥ 25 | 67(45.6) | 31(47.0) | 1.099(0.607–1.989) | 0.755 |
ASA score | ||||
 I | 14(9.4) | 5(7.6) | Ref |  |
 II | 121(81.8) | 52(78.8) | 1.203(0.412–3.514) | 0.735 |
 III | 13(8.8) | 8(12.1) | 1.723(0.447–6.636) | 0.429 |
 IV | 0(0) | 1(1.5) |  | 1 |
p T Stage | ||||
 0–2 | 89(60.1) | 40(60.6) | Ref |  |
 3–4 | 59(39.9) | 26(39.4) | 0.981(0.542–1.775) | 0.948 |
p N Stage | ||||
 0 | 117(79.1) | 52(78.8) | Ref |  |
 1–2 | 31(20.9) | 14(21.2) | 1.016(0.499–2.068) | 0.965 |
Diabetes mellitus | ||||
 No | 130(87.8) | 55(83.3) | Ref |  |
 Yes | 18(12.2) | 11(16.7) | 0.640–3.259 | 0.376 |
Hypertension | ||||
 No | 117(79.1) | 43(65.2) | Ref |  |
 Yes | 31(20.9) | 23(34.8) | 2.019(1.062–3.839) | 0.032 |
Preoperative albumin level (g/dl) | ||||
 ≥ 35 | 137(97.9) | 61(96.8) | Ref |  |
 < 35 | 3(2.1) | 2(3.2) | 1.497(0.244–9.190) | 0.663 |
Preoperative haemoglobin level (g/dl) | ||||
 ≥ 11 | 137(93.8) | 53(82.8) | Ref |  |
 < 11 | 9(6.2) | 11(17.2) | 3.159(1.239–8.058) | 0.016 |
Surgical technique | ||||
 Laparoscopic surgery | 50(33.8) | 24(36.4) | Ref |  |
 Open surgery | 98(66.2) | 42(63.6) | 0.893(0.487–1.637) | 0.714 |
Smoking | ||||
 No | 78(52.7) | 27(40.9) | Ref |  |
 Yes | 70(47.3) | 39(59.1) | 1.610(0.895–2.896) | 0.112 |
Bleeding volume (ml) | ||||
 ≤ 200 | 123(84.2) | 51(77.3) | Ref |  |
 > 200 | 23(15.8) | 15(22.7) | 1.573(0.760–3.257) | 0.223 |
Blood transfusion | ||||
 No | 137(92.6) | 54(81.8) | Ref |  |
 Yes | 11(7.4) | 12(18.2) | 2.768(1.152–6.650) | 0.023 |
Operation duration (min) | ||||
 ≤ 180 | 84(56.8) | 23(34.8) | Ref |  |
 > 180 | 64(43.2) | 43(65.2) | 2.454(1.344–4.479) | 0.003 |
Time interval between NCRT and APR | ||||
 ≤ 8 weeks | 76(51.4) | 22(33.3) | Ref |  |
 > 8 weeks | 72(48.6) | 44(66.7) | 2.111(1.153–3.865) | 0.015 |
Irradiation of IRF | ||||
 No | 94(63.5) | 30(45.5) | Ref |  |
 Yes | 54(36.5) | 36(54.5) | 2.089(1.159–3.764) | 0.014 |