Cost-effectiveness analysis of long-course oxaliplatin and bolus of fluorouracil based preoperative chemoradiotherapy vs. 5x5Gy radiation plus FOLFOX4 for locally advanced resectable rectal cancer

Table 1 Transition probabilities, unit costs, and utilities used in the analysis

Parameter	SCRT	LCCRT	Data source
Survival
3 year-DFS	53%	52%	Bujko et al. [8]
3-year OS	73%	65%	Bujko et al. [8]
Probabilities (monthly)
DFS to PD	0.0204	0.0244
DFS to Death	0.0148	0.0148
PD to Death	0.0348	0.1020
Costs per Cycle in US$
DFS state	444.85	461.34
PD state	4920.50	4920.50	Wen et al. [14]
Utility
DFS state	0.65	0.56	Ramsey et al. [15]
PD state	0.47	0.47	Wen et al. [14]
Death state	0.00	0.00

Abbreviations: SCRT Short-course radiotherapy, LCCRT Long-course chemoradiotherapy, DFS Disease-free survival, OS Overall survival, PD Progressive disease, m median

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