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Table 3 Acute and late toxicity

From: Accelerated hypofractionated radiotherapy plus chemotherapy for inoperable locally advanced non-small-cell lung cancer: final results of a prospective phase-II trial with a long-term follow-up

Toxicity (NCI CTCAE v 3.0)

Grade 1

Grade 2

Grade 3

Grade 4

Grade 5

n

%

n

%

n

%

n

%

n

%

Acute (n = 23)

 Neutropenia

–

–

2

12

–

–

12

70

–

–

 Leucopenya

–

–

–

–

5

29

4

24

–

–

 Anemy

–

–

2

12

–

–

–

–

–

–

 Mucosyte

–

–

2

12

–

–

–

–

–

–

 Creatinine

–

–

3

18

–

–

–

–

–

–

 Paresthesie

–

–

10

59

4

24

  

–

–

  Dyspnea

13

76

2

12

–

–

–

–

–

–

  Cough

10

59

3

18

–

–

–

–

–

–

  Fever

–

–

–

–

–

–

–

–

–

–

  Esophagitis

5

29

3

18

–

–

–

–

–

–

  Fatigue

–

–

3

18

2

12

–

–

–

–

  Pneumonitis

11

65

3

18

–

–

–

–

–

–

 Cardiac arrhythmia

    

1

4

    

 Unspecified causes

        

1

4

 Pulmonary Hemorragie

  

1

4

      

 Allergic reaction

    

2

12

    

 Pulmonary abscess

Late (n = 17)

 Dyspnea

3

18

1

6

4

24

–

   

 Cough

–

–

1

6

–

–

–

–

  

 Pneumonitis

7

41

–

–

–

–

–

–

  
  1. Data presented as number (n) and percentage of patients who developed toxicity. Acute toxicity was calculated for all the 23 patients enrolled