Ablative radiation therapy for locally advanced pancreatic cancer: techniques and results

Radiation Oncology

Table 1 Modern randomized trials of conventionally fractionated radiotherapy

Study	N	Treatment Arms		mOS (months)	2y OS
FFCD-SFRO [5]	119	60Gy/30 fractions + 5Fu + cis- > gem		8.6	~ 15%^a
FFCD-SFRO [5]	119	gem		13, p = 0.03	~ 21%^a
ECOG 4201 [8]	74	50.4Gy/28 fractions - > gem		11.1	12%
ECOG 4201 [8]	74	gem		9.2, p = 0.017	5%
LAP-07 [7]	269^b	gem+/−erlotinib ->	54Gy + cape	15.2	~ 25%^a
LAP-07 [7]	269^b	gem+/−erlotinib ->	gem	16.5, NS	~ 25%^a

^aEstimated from Kaplan-Meier curves
^bResults from the second randomization are shown (patients who did not progress on induction chemotherapy)

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