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Table 2 Univariate and multivariate analysis of PFS and OS in all patients

From: Efficacy of moderately hypofractionated simultaneous integrated boost intensity-modulated radiotherapy combined with temozolomide for the postoperative treatment of glioblastoma multiforme: a single-institution experience

Variable

Univariate

Multivariate

PFS

0S

PFS

OS

P

P

HR

95%CI

P

HR

95%CI

P

Sex

0.329

0.429

      

 Male

        

 Female

        

Age

0.026a

0.022a

      

 < 50

  

RL

  

RL

  

 ≥ 50

  

1.894

(1.049,3.419)

0.034

1.999

(1.072,3.727)

0.029

Extent of surgery

0.003a

0.040a

      

 PR

  

RL

  

RL

  

 CR

  

0.370

(0.198,0.692)

0.002

   

KPS scores

0.036a

0.000a

      

 90–100

     

RL

  

 80

     

0.273

(0.137,0.542)

0.000

  ≤ 70

     

0.265

(0.095,0.738)

0.011

Concomitant TMZ

0.945

0.113

      

 Yes

        

 No

        

TMZ cycles

0.016a

0.000a

      

 < 6

  

RL

  

RL

  

 ≥ 6

  

0.495

(0.275,0.890)

0.019

0.246

(0.124,0.488)

0.000

  1. Abbreviations: TMZ temozolomide, PR partial resection, CR complete resection, RL referent level
  2. aSignificant in univariate analysis