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Table 2 Clonogenic cell survival LQ fit parameters for photon (αx and βx) and helium ion beam (α and β) irradiation using the Renca cells in vitro with corresponding LETd derived from MC simulation. Data for both experiment A (pristine peaks) and experiment B (SOBPs) are provided

From: Biophysical modeling and experimental validation of relative biological effectiveness (RBE) for 4He ion beam therapy

Exp. αx [Gy−1] βx [Gy−2] (α/β)x [Gy] α [Gy−1] β [Gy−2] LETd [keV/μm]
A 0.034 (±0.004) 0.018 (±0.001) 1.79 0.039 (±0.013) 0.029 (±0.003) 5.33
A 0.034 (±0.004) 0.018 (±0.001) 1.79 0.094 (±0.012) 0.046 (±0.012) 14.81
B 0.050 (±0.064) 0.023 (±0.014) 2.17 0.076 (±0.083) 0.024 (±0.02) 4.78
B 0.050 (±0.064) 0.023 (±0.014) 2.17 0.150 (±0.071) 0.018 (±0.018) 10.18
B 0.050 (±0.064) 0.023 (±0.014) 2.17 0.201 (±0.048) 0.017 (±0.005) 15.37
B 0.050 (±0.064) 0.023 (±0.014) 2.17 0.305 (±0.144) 0.022 (±0.032) 26.52