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Table 2 Comparative baseline characteristics of patients, stratified according to presence of high-risk features, treatments and IDC-P status

From: Retrospective study on the benefit of adjuvant radiotherapy in men with intraductal carcinoma of prostate

  At least one high risk feature
(n = 145)
No high-risk feature
(n = 148)
RP + ART, IDC-P[+]
(n = 21)
RP + ART, IDC-P[−]
(n = 27)
RP only, IDC-P[+]
(n = 33)
RP only, IDC-P[−]
(n = 64)
P * RP only, IDC-P[+]
(n = 19)
RP only, IDC-P[−]
(n = 129)
P *
Mean age at diagnosis (S.D.) 60.9 (5.8) 62.1 (5.7) 62.3 (6.5) 61.7 (6.0) 0.848 63.3 (8.1) 62.1 (7.4) 0.554
Grade Group
 1 0 (0%) 2 (7%) 8 (24%) 26 (41%) < 0.001 8 (42%) 85 (66%) 0.134
 2 7 (33%) 15 (56%) 10 (30%) 31 (48%) 9 (47%) 36 (28%)
 3 8 (38%) 7 (26%) 11 (33%) 4 (6%) 2 (11%) 8 (6%)
 4 1 (5%) 0 (0%) 1 (3%) 1 (2%) 0 0
 5 5 (24%) 3 (11%) 3 (9%) 2 (3%) 0 0
Lymphovascular invasion 12 (57%) 9 (33%) 6 (18%) 7 (11%) < 0.001 1 (5%) 1 (1%) 0.241
Extraprostatic extension 20 (95%) 23 (85%) 22 (67%) 43 (67%) 0.026 0 0
Seminal vesicle invasion 9 (43%) 7 (26%) 6 (18%) 7 (11%) 0.013 0 0
Positive margins 12 (57%) 16 (59%) 17 (52%) 35 (56%) 0.942 0 0
Mean #of high-risk features (S.D.) 2.2 (1.0) 1.8 (0.8) 1.5 (0.7) 1.4 (0.6) < 0.001 0 0
Median follow-up (months) (I.Q.R.) 49 (30–67) 44 (23–65) 61 (24–123) 108 (56–153) < 0.001 89 (61–116) 118 (84–139) 0.685
Centre
 1 19 (91%) 20 (74%) 0 0 < 0.001 0 0
 2 2 (9%) 7 (26%) 33 (100%) 64 (100%) 19 129
  1. High-risk features: Grade groups 4–5, seminal vesicle invasion, positive margins, extraprostatic extension
  2. ART Adjuvant radiotherapy, IDC-P Intraductal carcinoma of the prostate, RP Radical prostatectomy, S.D. Standard deviation, I.Q.R. Interquartile range
  3. *Welch’s test for means, Fisher’s exact test for 2 × 2 tests, Pearson’s chi-square for categorical variables with more than 2 categories, Mann-Whitney U test and Kruskall-Wallis for medians