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Table 2 Locoregional recurrences

From: Salivary gland carcinoma (SGC) with perineural spread and/or positive resection margin – high locoregional control rates after photon (chemo) radiotherapy - experience from a monocentric analysis

Patient

Tumor histology /stage

Localisation of locoregional recurrence

In-Field

Pat.1

(male)

High-grade mucoepidermoid carcinoma of the parotid gland

pT3pN1(1/18)L1V1Pn1R0

Gingiva, Mandibula with infiltration of the skin, also disseminated lung metastases at the timepoint of diagnosis of locoregional recurrence

yes

Pat.2

(male)

Ductal adenocarcinoma of the parotid gland, high-grade

pT4pN2b(19/38)L1V0Pn1

R2 (detection of supraclavicular lymph node metastases before start of radiochemotherapy)

Recurrence in the parotid region with orbital infiltration, also disseminated bone metastases at the timepoint of diagnosis of locoregional recurrence

yes

Pat.3

(male)

Intermediate-grade mucoepidermoid carcinoma of the parotid gland

pT1pN2b(2/3)L0V0Pn0R1

Recurrence in the parotid region (R0 resection of recurrence was possible)

yes

Pat.4

(male)

Low-grade adenoidcystic carcinoma of the submandibular gland

pT3pN0(0/34)L0V0Pn1R1

Recurrence in the thyroid gland, diagnosis of lung metastases 13 months after diagnosis of locoregional recurrence

No

Pat.5

(male)

Ductal carcinoma of the parotid gland, high-grade

pT4pN2b(22/28)LxVxPn1R0

Contralateral lymph node metastases, diagnosis of lung and liver metastases 6 months after diagnosis of locoregional recurrence

no

Pat.6

(female)

High-grade adenoidcystic carcinoma of the sinus maxillaris on the left side with skull base and orbital infiltration

pT4cN1R2

Recurrence in sinus maxillaris

yes

Pat.7

(male)

High grade adenoidcystic arcinoma of the submandibular gland on the left side

pT3 pN0 (0/24) cM0 L0 V0 Pn1 R0

Recurrence in Sinus cavernosus, also disseminated lung metastases diagnosed 18 months before diagnosis of locoregional recurrence

Margin of radiation field