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Table 2 Average dose parameters for PTVmets according to the four planning modalities

From: Dosimetric evaluation of four whole brain radiation therapy approaches with hippocampus and inner ear avoidance and simultaneous integrated boost for limited brain metastases

  sIMRT dIMRT VMAT Tomo p value
D2% (Gy) 50.8 ± 2.1 50.9 ± 2.4 51.4 ± 2.7 50.2 ± 2.7 > 0.05
D98% (Gy) 47.3 ± 2.5 47.6 ± 2.4 46.8 ± 2.2 46.9 ± 2.3 > 0.05
Dmedian (Gy) 49.7 ± 2.5 49.7 ± 2.5 49.7 ± 2.5 49.3 ± 2.6 > 0.05
TC (%) 99.1 ± 1.0 99.4 ± 0.7 98.9 ± 1.6 97.1 ± 1.7 c,e,f
HI 0.071 ± 0.021 0.066 ± 0.012 0.091 ± 0.024 0.065 ± 0.023 b,d,f
CI 0.74 ± 0.10 0.73 ± 0.10 0.73 ± 0.13 0.71 ± 0.10 > 0.05
  1. Each value was calculated from the data for all 10 patients. Values are expressed as mean ± SD. sIMRT step-and-shoot intensity-modulated radiotherapy, dIMRT dynamic intensity-modulated radiation therapy, VMAT volumetric-modulated arc therapy, Tomo helical tomotherapy. a: sIMRT vs dIMRT, b: sIMRT vs VMAT, c: sIMRT vs Tomo, d: dIMRT vs VMAT, e: dIMRT vs Tomo, f: VMAT vs Tomo. If c is in the “p value” column, it means that there is statistical significance between sIMRT and Tomo