Table 2 Patient Characteristics and Correspondences between ALBI grades and CTP scores

N

219

347

28

Gender

Male

188 (85.8%)

298 (85.9%)

25 (89.3%)

0.88

Pearson’s chi-squared

Age, mean (SD)

53.1918 (13.0342)

54.9885 (12.4969)

53.8571 (10.9636)

0.25

ANOVA

Prior-treatment

Yes

111 (50.7%)

183 (52.7%)

12 (42.9%)

0.57

Pearson’s chi-squared

Hepatitis B virus surface antigen

Positive

151 (68.9%)

248 (71.5%)

19 (67.9%)

0.97

Pearson’s chi-squared

Negative

37 (16.9%)

53 (15.3%)

5 (17.9%)

Unknow

31 (14.2%)

46 (13.3%)

4 (14.3%)

Hepatitis C virus status

Positive

2 (0.9%)

4 (1.1%)

0 (0.0%)

–

PT, mean (SD)

12.9216 (1.08293)

13.8273 (1.52867)

16.3407 (2.93353)

< 0.001

ANOVA

Total bilirubin, mean (SD)

12.5096 (5.46543)

19.0009 (14.5374)

91.4571 (150.022)

< 0.001

ANOVA

Albumin, mean (SD)

42.1589 (3.23209)

34.6175 (3.30602)

26.2357 (2.968)

< 0.001

ANOVA

Direct bilirubin, mean (SD)

5.83333 (13.6228)

9.76974 (10.4189)

56.6179 (90.1434)

< 0.001

ANOVA

AST, mean (SD)

36.7945 (32.4975)

50.2781 (38.2566)

79.3929 (59.5373)

< 0.001

ANOVA

ALT, mean (SD)

33.5342 (26.089)

46.7867 (52.4872)

52.5 (40.2386)

0.001

ANOVA

ALBI score, mean (SD)

−2.88589 (.25688)

−2.15091 (.306301)

−1.11186 (.279759)

< 0.001

ANOVA

CTP score

5

206 (94.1%)

123 (35.4%)

0 (0.0%)

< 0.001

Pearson’s chi-squared

6

11 (5.0%)

139 (40.1%)

0 (0.0%)

7

2 (0.9%)

59 (17.0%)

7 (25.0%)

8

0 (0.0%)

20 (5.8%)

7 (25.0%)

9

0 (0.0%)

5 (1.4%)

8 (28.6%)

10

0 (0.0%)

1 (0.3%)

3 (10.7%)

11

0 (0.0%)

0 (0.0%)

2 (7.1%)

13

0 (0.0%)

0 (0.0%)

1 (3.6%)

BCLC stage

1

108 (49.5%)

121 (34.9%)

6 (21.4%)

< 0.001

Pearson’s chi-squared

2

41 (18.8%)

68 (19.6%)

4 (14.3%)

3

69 (31.7%)

157 (45.2%)

11 (39.3%)

4

0 (0.0%)

1 (0.3%)

7 (25.0%)

Tumor size, mean (SD)

5.72055 (6.40287)

6.85101 (4.83619)

6.68929 (4.26383)

0.054

ANOVA

Hemoglobin, mean (SD)

134.988 (17.6542)

119.383 (19.2401)

101.955 (22.4)

< 0.001

ANOVA

Platelet, mean (SD)

175.485 (71.4823)

172.494 (96.402)

131.5 (117.778)

0.092

ANOVA

Red blood cell, mean (SD)

4.64133 (.662971)

4.15443 (.725179)

3.47409 (.717799)

< 0.001

ANOVA

White blood cell, mean (SD)

6.19509 (2.65843)

6.41506 (3.22305)

5.82591 (2.94477)

0.57

ANOVA

AFP status (ng/mL)

Unknow

16 (7.3%)

12 (3.5%)

0 (0.0%)

0.049

Pearson’s chi-squared

< 8

64 (29.2%)

83 (23.9%)

5 (17.9%)

8–200

59 (26.9%)

102 (29.4%)

13 (46.4%)

> 200

80 (36.5%)

150 (43.2%)

10 (35.7%)

Total dose (Gy), median (IQR)

43 (42, 45)

42 (40, 45)

42 (39, 45)

0.13

Kruskal-Wallis

Fractions

1

3 (1.4%)

3 (0.9%)

0 (0.0%)

0.69

Pearson’s chi-squared

2

3 (1.4%)

3 (0.9%)

1 (3.6%)

3

136 (62.1%)

188 (54.2%)

16 (57.1%)

4

57 (26.0%)

114 (32.9%)

9 (32.1%)

5

19 (8.7%)

35 (10.1%)

2 (7.1%)

6

1 (0.5%)

4 (1.2%)

0 (0.0%)

BED10, median (IQR)

100.8 (89.7, 112.5)

94.0062 (86.1, 100.8)

94.0125 (87.9, 100.8)

< 0.001

Kruskal-Wallis

EQD2, median (IQR)

84 (74.75, 93.75)

78.3385 (71.75, 84)

78.3438 (73.25, 84)

< 0.001

Kruskal-Wallis