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Table 1 Patient and tumor characteristics at first-line and second-line treatment, n = 75

From: Salvage radiotherapy for recurrent hypopharyngeal and laryngeal squamous cell carcinoma (SCC) after first-line treatment with surgery alone: a 10-year single-centre experience

characteristic No. (%)
first-line treatment (surgery) second-line treatment (RT/CRT)
median age (years) 59 (42–83) 62 (46–83)
gender
 male 64 (85) 64 (85)
 female 11 (15) 11 (15)
Karnofsky performance score in %
 100 25 (33) 12 (16)
 90 18 (24) 23 (31)
 80 24 (32) 17 (23)
 70 8 (11) 17 (23)
 60 none 6 (8)
tumor site
 glottic larynx 46 (61) 31 (41)
 subglottic larynx 3 (4) 10 (13)
 supraglottic larynx 12 (16) 8 (11)
 hypopharynx 14 (19) 14 (19)
 neopharynx none 12 (16)
UICC stage
 I 20 (27) 16 (21)
 II 22 (29) 8 (11)
 III 9 (12) 21 (28)
 IVA 22 (29) 19 (25)
 IVB 1 (1) 10 (13)
 IVC 1 (1) 1 (1)
TNM stage
 T1 22 (29) 22 (29)
 T2 25 (33) 12 (16)
 T3 14 (19) 15 (20)
 T4 14 (19) 26 (35)
 N0 51 (68) 48 (64)
 N1 3 (4) 11 (15)
 N2 20 (27) 14 (19)
 N3 1 (1) 1 (1)
 M0 74 (99) 73 (97)
 M1 1 (1) 2 (3)
G stage
 G1 2 (3) 2 (3)
 G2 51 (68) 49 (65)
 G3 19 (25) 21 (28)
 Gx 3 (4) 3 (4)
  1. abbreviations: RT radiotherapy, CRT chemoradiotherapy, T tumor stage, N nodal stage, M metastasis stage, G grading, UICC Union Internationale Contre le Cancer