Table 1 Patient and tumor characteristics at first-line and second-line treatment, n = 75
characteristic | No. (%) | |
|---|---|---|
first-line treatment (surgery) | second-line treatment (RT/CRT) | |
median age (years) | 59 (42–83) | 62 (46–83) |
gender | ||
 male | 64 (85) | 64 (85) |
 female | 11 (15) | 11 (15) |
Karnofsky performance score in % | ||
 100 | 25 (33) | 12 (16) |
 90 | 18 (24) | 23 (31) |
 80 | 24 (32) | 17 (23) |
 70 | 8 (11) | 17 (23) |
 60 | none | 6 (8) |
tumor site | ||
 glottic larynx | 46 (61) | 31 (41) |
 subglottic larynx | 3 (4) | 10 (13) |
 supraglottic larynx | 12 (16) | 8 (11) |
 hypopharynx | 14 (19) | 14 (19) |
 neopharynx | none | 12 (16) |
UICC stage | ||
 I | 20 (27) | 16 (21) |
 II | 22 (29) | 8 (11) |
 III | 9 (12) | 21 (28) |
 IVA | 22 (29) | 19 (25) |
 IVB | 1 (1) | 10 (13) |
 IVC | 1 (1) | 1 (1) |
TNM stage | ||
 T1 | 22 (29) | 22 (29) |
 T2 | 25 (33) | 12 (16) |
 T3 | 14 (19) | 15 (20) |
 T4 | 14 (19) | 26 (35) |
 N0 | 51 (68) | 48 (64) |
 N1 | 3 (4) | 11 (15) |
 N2 | 20 (27) | 14 (19) |
 N3 | 1 (1) | 1 (1) |
 M0 | 74 (99) | 73 (97) |
 M1 | 1 (1) | 2 (3) |
G stage | ||
 G1 | 2 (3) | 2 (3) |
 G2 | 51 (68) | 49 (65) |
 G3 | 19 (25) | 21 (28) |
 Gx | 3 (4) | 3 (4) |