From: 3-weekly or weekly cisplatin concurrently with radiotherapy for patients with squamous cell carcinoma of the head and neck – a multicentre, retrospective analysis
3-weekly Cisplatin
Weekly Cisplatin
p-value
Median cumulative cisplatin dose
200 mg/m2
160 mg/m2
< 0.001
Cumulative dose ≥200 mg2
96 (75.6%)
88 (47.1%)
Dose reduction
6 (4.7%)
11 (5.8%)
Change to other chemotherapy
33 (25.9%)
35 (18.7%)