|
Number of Patients
|
Median follow-up (month, range)
|
Treatment
|
Median total dose
|
Grade ≥ 4 RP
|
---|
Yamashita et al.
|
13
|
14.7 (0.3–76.2)
|
SBRT
|
48.0 Gy
|
7 (53.8%)
|
Lee et al.
|
14
|
15.5 (6.1–40.9)
|
3DCRT
|
56.9 Gy
|
5 (35.7%)
|
Yamaguchi et al.
|
16
|
–
|
SBRT
|
48.0 Gy
|
2 (12.5%)
|
Ono et al.
|
16
|
12.0 (4–39)
|
PBT
|
80.0 Gy (RBE)
|
1 (6.3%)
|
Current study
|
30
|
11.0 (2–51)
|
X-raya/PBT
|
60.0 Gy
|
18.2% (4/22) in X-ray 0% (0/8) in PBT
|
- RP radiation pneumonitis, IPF idiopathic pulmonary fibrosis, SBRT stereotactic body radiation therapy, 3DCRT 3-dimensional conformal radiation therapy, PBT proton beam therapy
- aX-ray treatment includes 3DCRT, SBRT, and intensity-modulated radiation therapy (IMRT)