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Table 4 Clinical courses of patients with fatal treatment-related death

From: Preliminary result of definitive radiotherapy in patients with non-small cell lung cancer who have underlying idiopathic pulmonary fibrosis: comparison between X-ray and proton therapy

No.

Age/Sex

PS

Smoking

FEV1 / DLCO

Underlying disease

Stage

RT technique

Time to TRC (months)

Survival (months)

1

77/M

1

Ex-, 30PY

2.2 L, 84% / 58%

IPF and COPD

T2a N0

3DCRT 60 Gy/15 Fx’s

3

4

2

79/M

2

Ex-, 40PY

2.3 L, 85% / 77%

IPF

T1b N1

3DCRT 60 Gy/15 Fx’s

2

3

3

78/M

2

Ex-, 100PY

2.5 L, 131% / 60%

IPF and COPD

T2a N0

SBRT, 60 Gy/4 Fx’s

2

8

4

69/M

1

Ex-, 120PY

2.0 L, 78% / 31%

IPF

T2a N0

SBRT 60 Gy/4 Fx’s

4

5

  1. PS performance status, PY pack-year, FEV1 forced expiratory volume in 1 s, DLCO diffusing capacity of the lung for carbon monoxide, IPF idiopathic pulmonary fibrosis, COPD chronic obstructive pulmonary disease, RT radiation therapy, 3DCRT 3-dimensional conformal radiation therapy, SBRT stereotactic body radiation therapy, TRC treatment-related complications