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Table 4 Clinical courses of patients with fatal treatment-related death

From: Preliminary result of definitive radiotherapy in patients with non-small cell lung cancer who have underlying idiopathic pulmonary fibrosis: comparison between X-ray and proton therapy

No. Age/Sex PS Smoking FEV1 / DLCO Underlying disease Stage RT technique Time to TRC (months) Survival (months)
1 77/M 1 Ex-, 30PY 2.2 L, 84% / 58% IPF and COPD T2a N0 3DCRT 60 Gy/15 Fx’s 3 4
2 79/M 2 Ex-, 40PY 2.3 L, 85% / 77% IPF T1b N1 3DCRT 60 Gy/15 Fx’s 2 3
3 78/M 2 Ex-, 100PY 2.5 L, 131% / 60% IPF and COPD T2a N0 SBRT, 60 Gy/4 Fx’s 2 8
4 69/M 1 Ex-, 120PY 2.0 L, 78% / 31% IPF T2a N0 SBRT 60 Gy/4 Fx’s 4 5
  1. PS performance status, PY pack-year, FEV1 forced expiratory volume in 1 s, DLCO diffusing capacity of the lung for carbon monoxide, IPF idiopathic pulmonary fibrosis, COPD chronic obstructive pulmonary disease, RT radiation therapy, 3DCRT 3-dimensional conformal radiation therapy, SBRT stereotactic body radiation therapy, TRC treatment-related complications